Silence Therapeutics at TIDES Europe 2026

Nov 3–5, 2026 Amsterdam, Netherlands ~900 attendees Website

Silence Therapeutics takes part in 2 sessions at TIDES Europe 2026 in Amsterdam. Its sessions cover siRNA design and an obesity application. It revisits end stabilization to extend siRNA duration of action through nuclease resistance, and presents SLN098, an siRNA that silences the genetically validated target INHBE to enhance fat loss while preserving lean mass.

OrganizationTIDES Europe 2026 Attendance
Silence Therapeutics
London, United Kingdom
Biotech
Develops siRNA medicines using its mRNAi GOLD platform for cardiovascular, haematological and other diseases.
Talk
Wed Nov 4
10:15–10:45
Elongating siRNA Duration of Action by Enhanced Nuclease Resistance: End Stabilization Revisited
A modification near each end of a siRNA made gene silencing in mice last longer while needing fewer sulfur linkages.
Talk
Fri Nov 6
11:35–12:00
Presentation: Genetically-Validated INHBE Silencing with SLN098 siRNA for Enhanced Fat Loss and Lean Mass Preservation
Post-event symposium: Clinical & Translational Updates

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