Icahn School of Medicine at Mount Sinai at SfN 2026

Nov 14–18, 2026 Washington, DC ~21k attendees Website

Icahn School of Medicine at Mount Sinai brings 73 presentations to SfN 2026 in Washington. Its SfN 2026 presentations centre on stress and resilience, decision-making and addiction, and brain changes in Alzheimer’s and Parkinson’s disease. One thread examines how brain-reactive antibodies may connect meningeal lymphatic activity with stress-related behavioral susceptibility.

Organization	SfN 2026 Attendance
Icahn School of Medicine at Mount Sinai New York, NY
mssm.edu Universities and research institutes Medical school and biomedical research institution in New York City, affiliated with the Mount Sinai Health System.	Poster Sat Nov 14 1–5pm Part of Session PSTR022: Stress: Neuroimmunology Stress-induced brain-reactive IgG links meningeal lymphatic activation to perivascular brain entry and behavioral susceptibility WCC Halls A-C · Board CC4 Poster Sat Nov 14 1–5pm Part of Session PSTR026: Depression and Anxiety A conserved nucleus accumbens transcriptional network defines stress resilience across sex WCC Halls A-C · Board DD26 Poster Sat Nov 14 1–5pm Part of Session PSTR027: Mechanisms of Learning and Memory in the Context of Addiction Nucleus accumbens and basolateral amygdala ensembles differentially mediate cocaine seeking after abstinence WCC Halls A-C · Board EE13 Poster Sat Nov 14 1–5pm Part of Session PSTR038: Neurodegenerative Diseases (AD, PD, MS, Stroke) Differential Relationship Between DTI-ALPS and Motor Improvement Across STN and GPi Deep Brain Stimulation Targets in Parkinson’s Disease WCC Halls A-C · Board KK47 Poster Sat Nov 14 1–5pm Part of Session PSTR039: Gene, Protein, or Cell Based Approaches A humanized follicle stimulating hormone blocking antibody as a therapeutic strategy for osteoporosis, obesity, and Alzheimer's disease WCC Halls A-C · Board LL2 Poster Sun Nov 15 8am–noon Part of Session LBP002: C.02. Alzheimer's Disease and Other Dementias Neocortical region-specific remodeling of astrocyte interactions with neurons and vasculature tracks with Alzheimer’s disease progression WCC Halls A-C · Board B10 Poster Sun Nov 15 8am–noon Part of Session LBP003: C.03. Parkinson’s Disease A Bilateral Intranigral AAV-A53T α-Synuclein Mouse Model of Parkinson's Disease for Investigating the Role of Follicle-Stimulating Hormone WCC Halls A-C · Board C23 Poster Sun Nov 15 8am–noon Part of Session LBP003: C.03. Parkinson’s Disease Distinct substantia nigra neuron subtypes linked to selective vulnerability in Parkinson’s disease WCC Halls A-C · Board C27 Poster Sun Nov 15 8am–noon Part of Session PSTR065: Adolescent Stress: Behavior and Physiology Resting Heart Rate Moderates the Association Between PM2.5 Exposure and Anxiety Symptoms in Adolescents WCC Halls A-C · Board EE21 Poster Sun Nov 15 8am–noon Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making A neuroeconomic approach to study deliberative prosocial decision-making in mice WCC Halls A-C · Board HH18 Poster Sun Nov 15 8am–noon Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making The ventral tegmental area and dorsal raphe nucleus control neuroeconomically distinct choice behavior WCC Halls A-C · Board HH19 Poster Sun Nov 15 8am–noon Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making Toward a cross-species model of social-cognitive maps WCC Halls A-C · Board HH21 Poster Sun Nov 15 8am–noon Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making Developing a task to probe how internal state changes affect hippocampal spatial codes WCC Halls A-C · Board HH22 Poster Sun Nov 15 8am–noon Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making A neuroeconomic approach to understanding decision-making behavior in a mouse model of binge-eating disorder WCC Halls A-C · Board HH24 Poster Sun Nov 15 8am–noon Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making Characterizing the effects of GLP-1 agonists (semaglutide) on neuroeconomic decision-making behavior in a mouse model of binge eating disorder WCC Halls A-C · Board HH25 Lecture Sun Nov 15 noon–1pm Part of Session LEC07: Clinical Neuroscience Lecture: Mending the Mind: From Single Neurons to Memory Neuroprosthetics Moderator WCC Hall D Poster Sun Nov 15 1–5pm Part of Session LBP009: H.03. Motivation Neuroeconomically dissociable decision-making computations are altered by Shank3 haploinsufficiency WCC Halls A-C · Board B28 Poster Sun Nov 15 1–5pm Part of Session PSTR084: Transcription and Translation in Plasticity Quinone reductase 2 reads H3 serotonylation to support neuronal maturation WCC Halls A-C · Board L6 Poster Sun Nov 15 1–5pm Part of Session PSTR084: Transcription and Translation in Plasticity Ketamine Induces a Sustained Increase in Histone H3 Serotonylation that Outlasts Its Acute Transcriptional Wave in the mPFC WCC Halls A-C · Board L8 Poster Sun Nov 15 1–5pm Part of Session PSTR084: Transcription and Translation in Plasticity The estrous cycle regulates histone serotonylation-associated gene expression patterns in the dorsal raphe nucleus WCC Halls A-C · Board M2 Poster Sun Nov 15 1–5pm Part of Session PSTR084: Transcription and Translation in Plasticity Histone serotonylation recruitment of KMT2E regulates chromatin dynamics in neurodevelopment WCC Halls A-C · Board M3 Poster Sun Nov 15 1–5pm Part of Session PSTR093: Stroke Recovery: Mechanisms and Pharmacological Approaches Targeting NETs Enhances Penumbra Reperfusion and Oxygenation After Ischemic Stroke in Aged Mice WCC Halls A-C · Board V22 Poster Sun Nov 15 1–5pm Part of Session PSTR110: Neural Mechanisms of Human Social Cognition Neurocomputational mechanisms of social norm learning in human prefrontal cortices WCC Halls A-C · Board HH5 Poster Sun Nov 15 1–5pm Part of Session PSTR113: Genomic and Transcriptomic Techniques (Non-Human) Single-chromatin fiber profiling links rDNA enhancer repeat variation to distinct epigenetic and transcriptional states in the mouse hippocampus WCC Halls A-C · Board II24 Talk Sun Nov 15 2–4:30pm Part of Session MIN12: Embodied Computation: How Does Embodiment Impact Sensorimotor and Cognitive Processing Chair WCC Rm 151 Poster Mon Nov 16 8am–noon Part of Session PSTR124: Oligodendrocytes Development Long-read Nanopore DNA sequencing reveals developmental and cell-type-specific DNA methylation and hydroxymethylation landscapes in human OPCs and oligodendrocytes WCC Halls A-C · Board Q5 Poster Mon Nov 16 8am–noon Part of Session PSTR149: Mechanisms of Cocaine Use and Addiction H2A.Z dysregulation during cocaine withdrawal modulates drug relapse behavior WCC Halls A-C · Board GG8 Poster Mon Nov 16 8am–noon Part of Session PSTR151: Neural and Behavioral Mechanisms of Opioid Seeking, Withdrawal, and Relapse Divergent transcriptional states distinguish high- and low-escalating oral oxycodone self-administration and persist into protracted abstinence WCC Halls A-C · Board II6 Poster Mon Nov 16 8am–noon Part of Session PSTR152: Neural Substrates of Opioid Seeking Multi-omic profiling of synthetic and non-synthetic opioid withdrawal reveals sex-specific epigenetic reprogramming of the nucleus accumbens WCC Halls A-C · Board JJ10 Poster Mon Nov 16 8am–noon Part of Session PSTR155: Behavioral and Circuit Mechanisms of Social Behavior II Stress reshapes social motivation through altered anterior cingulate cortex dynamics WCC Halls A-C · Board KK35 Talk Mon Nov 16 8:15–8:30am Part of Session NANO19: Neural and Molecular Mechanisms of Addictive Drugs Dopaminoceptive cells in the ventral hippocampus control cocaine action WCC Rm 143 Session Mon Nov 16 9–10am Part of Session MTE06: Meet-the-Expert: Russo — Building a Translational Research Program to Study the Neuroimmune Mechanisms of Depression Moderator WCC Rm 201 Session Mon Nov 16 10:30am–noon Part of Session BTCR01: Overlap of GLP-1 Circuitry in Addiction and Obesity: Treatment Implications Speaker WCC Rm 152 Poster Mon Nov 16 1–5pm Part of Session PSTR194: Post-Traumatic Stress Disorder and Other Psychiatric Disorders: Human Studies and Therapeutic Approaches Single-Nucleus Transcriptomic Profiling Reveals Disease- and Age-Associated Molecular Programs in the Human Ventral Midbrain WCC Halls A-C · Board GG7 Poster Mon Nov 16 1–5pm Part of Session PSTR196: Pharmacological and Molecular Mechanisms in Substance Use Disorders Effects of GLP-1R Deletion in Triangular Septal Nucleus Neurons on the Motivational Properties of Nicotine WCC Halls A-C · Board HH8 Poster Mon Nov 16 1–5pm Part of Session PSTR204: Multi-Omics Spatial Transcriptomic Niche Trajectories Reveal Coordinated Gene and Cell-Cell Communication Dynamics Across the Whole Mouse Brain WCC Halls A-C · Board LL36 Talk Mon Nov 16 3:45–4pm Part of Session NANO25: Value, Memory, and Social Inference: Multi-Circuit Dynamics of Human Cognition Shared neural dynamics underpin social belief inference WCC Rm 143 Poster Tue Nov 17 8am–noon Part of Session LBP051: B.10. Neuro-Oncology Plexin Receptors Control Coupling of Neuronal Activity to Glioblastoma Progression WCC Halls A-C · Board C60 Poster Tue Nov 17 8am–noon Part of Session LBP051: B.10. Neuro-Oncology KDM6B-mediated epigenetic-metabolic reprogramming shapes the immunosuppressive landscape in Glioblastoma WCC Halls A-C · Board C61 Poster Tue Nov 17 8am–noon Part of Session PSTR216: Astrocytes: Signaling, Synaptic Regulation, and Circuit Function Modulating astrocyte endfeet to increase blood-brain-barrier permeability WCC Halls A-C · Board Q5 Poster Tue Nov 17 8am–noon Part of Session PSTR218: Brain Wellness and Aging Investigating Microglial Plasticity and Function in Brain Aging WCC Halls A-C · Board T11 Poster Tue Nov 17 8am–noon Part of Session PSTR218: Brain Wellness and Aging Lifespan single-cell transcriptomic atlas of the human prefrontal cortex WCC Halls A-C · Board T13 Poster Tue Nov 17 8am–noon Part of Session PSTR218: Brain Wellness and Aging Single-molecule profiling of mitochondrial DNA accessibility in human and mouse brain WCC Halls A-C · Board T15 Poster Tue Nov 17 8am–noon Part of Session PSTR218: Brain Wellness and Aging Altered Cerebral White and Gray Matter Volumes during Aging and Vascular Disease in Great Apes WCC Halls A-C · Board U4 Poster Tue Nov 17 8am–noon Part of Session PSTR219: Metabolic and Neural Changes Across Brain Aging: Experimental Models Age-related changes to the ultrastructure of myelinated axons and neuroprotective effect of dietary curcumin in the lateral prefrontal cortex layer 3 of the rhesus monkey WCC Halls A-C · Board U18 Poster Tue Nov 17 8am–noon Part of Session PSTR244: Cocaine: Reinforcement, Seeking, Reinstatement, and Memory Effects of Chronic Cocaine Exposure on Approach/Avoidance Decision-Making WCC Halls A-C · Board KK20 Poster Tue Nov 17 8am–noon Part of Session PSTR245: Clinical and Applied Mechanisms of Attention in Humans Neural basis of improved sustained attention following sleep apnea treatment WCC Halls A-C · Board KK56 Talk Tue Nov 17 1–2:45pm Part of Session NANO33: Neuronal Mechanisms of Misophonia Chair WCC Rm 140 Poster Tue Nov 17 1–5pm Part of Session PSTR284: Cocaine: Cell Signaling, Plasticity, Circuitry, and Glial Mechanisms Synaptic neuroproteomic signatures of cocaine withdrawal across mesocorticolimbic brain regions WCC Halls A-C · Board JJ16 Poster Tue Nov 17 1–5pm Part of Session PSTR284: Cocaine: Cell Signaling, Plasticity, Circuitry, and Glial Mechanisms Sex- and Withdrawal-Dependent Remodeling of the Synaptic Proteome in the Nucleus Accumbens After Cocaine Exposure Reveals Ephexin1 as a Regulator of Cocaine Seeking WCC Halls A-C · Board JJ17 Poster Tue Nov 17 1–5pm Part of Session PSTR284: Cocaine: Cell Signaling, Plasticity, Circuitry, and Glial Mechanisms Circuit and transcriptomic mechanisms for dopamine receptor D2-expressing neurons in paraventricular nucleus of the thalamus: Role in cocaine-seeking behavior WCC Halls A-C · Board KK4 Talk Tue Nov 17 2:30–2:45pm Part of Session NANO33: Neuronal Mechanisms of Misophonia Impaired Reversal Learning in Misophonia: Behavioral and Neural Evidence from EEG WCC Rm 140 Poster Wed Nov 18 8am–noon Part of Session LBP076: J.06. Computation, Modeling, and Simulation Inferring neuromodulatory credit assignment in recurrent neural networks WCC Halls A-C · Board C8 Talk Wed Nov 18 8–11:15am Part of Session NANO42: Sleep Systems in Health and Disease Chair WCC Rm 140 Poster Wed Nov 18 8am–noon Part of Session PSTR297: Animal Models of Autism Neural basis of pharmacological amelioration of social deficits in Fmr1KO mice during juvenile sensitive period WCC Halls A-C · Board D17 Poster Wed Nov 18 8am–noon Part of Session PSTR304: Alzheimer's Disease: Therapeutic Strategies: Amyloidosis Models Effects of Intranasal VGF Derived TLQP-21 on Early- and Late-Stage Pathology in 5xFAD Model of Alzheimer's Disease WCC Halls A-C · Board Web Only Poster Wed Nov 18 8am–noon Part of Session PSTR307: Ataxias and Dystonia Neurodegeneration and Inflammation in a Novel Spinocerebellar Ataxia 13 Preclinical Model WCC Halls A-C · Board W24 Poster Wed Nov 18 8am–noon Part of Session PSTR321: Stress-Modulated Pathways: Anatomy, Physiology, Neurochemistry Hormonal regulation of stress resilience through ERα-dependent plasticity mechanisms WCC Halls A-C · Board FF23 Poster Wed Nov 18 8am–noon Part of Session PSTR324: Anxiety Disorders: Preclinical and Human Studies, Mechanisms, and Interventions Neural Correlates of Day-to-Day Affective Variability: Frontopolar Involvement in Mood and Anxiety Disorders WCC Halls A-C · Board II1 Talk Wed Nov 18 10–10:15am Part of Session NANO42: Sleep Systems in Health and Disease Neocortical long-range inhibition promotes cortical synchrony and sleep WCC Rm 140 Talk Wed Nov 18 10:45–11:20am Part of Session SYM14: Cross-Species Approaches to Understanding Human Cognition Primate ventral frontal cortex contributions to decision-making WCC Rm 151 Poster Wed Nov 18 1–5pm Part of Session LBP087: I.09. Spatial Navigation The Earliest Signs of Cognitive Aging: Declining Precision, Stability, and Flexibility in Hippocampal Memory WCC Halls A-C · Board C42 Poster Wed Nov 18 1–5pm Part of Session LBP088: I.10. Human Learning and Cognition Social context shapes orbitofrontal responses to hippocampal sharp-wave ripples during human social navigation WCC Halls A-C · Board C52 Poster Wed Nov 18 1–5pm Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States Progression of medial entorhinal spatial coding deficits in a mouse model of temporal lobe epilepsy WCC Halls A-C · Board N3 Poster Wed Nov 18 1–5pm Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States Medial entorhinal layer 2 stellate cell activity is sufficient to drive type 2 dentate spikes and pathological hypersynchronous events in healthy and epileptic mice WCC Halls A-C · Board N4 Poster Wed Nov 18 1–5pm Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States Interneuron theta phase locking controls seizure susceptibility WCC Halls A-C · Board N5 Poster Wed Nov 18 1–5pm Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States Circuit editing to boost long-range feedforward inhibition decreases chronic seizures in experimental temporal lobe epilepsy WCC Halls A-C · Board N6 Poster Wed Nov 18 1–5pm Part of Session PSTR355: Viral and Infectious Mechanisms of Neuroinflammation II Genetic dissection of acute and long-term anosmia following SARS-CoV-2 infection WCC Halls A-C · Board X21 Poster Wed Nov 18 1–5pm Part of Session PSTR369: Sleep: Human Behavioral Studies Time-on-task effects in sleep apnea patients on and off treatment WCC Halls A-C · Board GG16 Poster Wed Nov 18 1–5pm Part of Session PSTR374: Neural Mechanisms of Stress and Depression in Animal Models Single chromatin fiber and transcriptomic profiling of the 'postpartum' mouse brain WCC Halls A-C · Board JJ8 Poster Wed Nov 18 1–5pm Part of Session PSTR380: Hippocampal Dynamics and Coding Prior experience accelerates reward over-representation in novel environments to support learning-to-learn WCC Halls A-C · Board LL28 Talk Wed Nov 18 1:15–1:30pm Part of Session NANO46: Molecular Physiology of Ligand-Gated Receptors and Ion Channels Neurotransmission N-Glycosylation Profiles in Dorsolateral Prefrontal Cortex of Individuals with Major Depression and Bipolar Disorder WCC Rm 140 Talk Wed Nov 18 3:37–4pm Part of Session MIN35: Paired Neuroimaging and Brain Omics From the Same Individuals for Disease Mechanisms and Diagnostics Establishing the relationship between brain cellular senescence and brain structure WCC Rm 147

Organization

SfN 2026 Attendance

Icahn School of Medicine at Mount Sinai

New York, NY

mssm.edu

Universities and research institutes

Medical school and biomedical research institution in New York City, affiliated with the Mount Sinai Health System.

Poster

Sat Nov 14
1–5pm

Part of Session PSTR022: Stress: Neuroimmunology

Stress-induced brain-reactive IgG links meningeal lymphatic activation to perivascular brain entry and behavioral susceptibility

WCC Halls A-C · Board CC4

Poster

Sat Nov 14
1–5pm

Part of Session PSTR026: Depression and Anxiety

A conserved nucleus accumbens transcriptional network defines stress resilience across sex

WCC Halls A-C · Board DD26

Poster

Sat Nov 14
1–5pm

Part of Session PSTR027: Mechanisms of Learning and Memory in the Context of Addiction

Nucleus accumbens and basolateral amygdala ensembles differentially mediate cocaine seeking after abstinence

WCC Halls A-C · Board EE13

Poster

Sat Nov 14
1–5pm

Part of Session PSTR038: Neurodegenerative Diseases (AD, PD, MS, Stroke)

Differential Relationship Between DTI-ALPS and Motor Improvement Across STN and GPi Deep Brain Stimulation Targets in Parkinson’s Disease

WCC Halls A-C · Board KK47

Poster

Sat Nov 14
1–5pm

Part of Session PSTR039: Gene, Protein, or Cell Based Approaches

A humanized follicle stimulating hormone blocking antibody as a therapeutic strategy for osteoporosis, obesity, and Alzheimer's disease

WCC Halls A-C · Board LL2

Poster

Sun Nov 15
8am–noon

Part of Session LBP002: C.02. Alzheimer's Disease and Other Dementias

Neocortical region-specific remodeling of astrocyte interactions with neurons and vasculature tracks with Alzheimer’s disease progression

WCC Halls A-C · Board B10

Poster

Sun Nov 15
8am–noon

Part of Session LBP003: C.03. Parkinson’s Disease

A Bilateral Intranigral AAV-A53T α-Synuclein Mouse Model of Parkinson's Disease for Investigating the Role of Follicle-Stimulating Hormone

WCC Halls A-C · Board C23

Poster

Sun Nov 15
8am–noon

Part of Session LBP003: C.03. Parkinson’s Disease

Distinct substantia nigra neuron subtypes linked to selective vulnerability in Parkinson’s disease

WCC Halls A-C · Board C27

Poster

Sun Nov 15
8am–noon

Part of Session PSTR065: Adolescent Stress: Behavior and Physiology

Resting Heart Rate Moderates the Association Between PM2.5 Exposure and Anxiety Symptoms in Adolescents

WCC Halls A-C · Board EE21

Poster

Sun Nov 15
8am–noon

Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making

A neuroeconomic approach to study deliberative prosocial decision-making in mice

WCC Halls A-C · Board HH18

Poster

Sun Nov 15
8am–noon

Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making

The ventral tegmental area and dorsal raphe nucleus control neuroeconomically distinct choice behavior

WCC Halls A-C · Board HH19

Poster

Sun Nov 15
8am–noon

Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making

Toward a cross-species model of social-cognitive maps

WCC Halls A-C · Board HH21

Poster

Sun Nov 15
8am–noon

Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making

Developing a task to probe how internal state changes affect hippocampal spatial codes

WCC Halls A-C · Board HH22

Poster

Sun Nov 15
8am–noon

Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making

A neuroeconomic approach to understanding decision-making behavior in a mouse model of binge-eating disorder

WCC Halls A-C · Board HH24

Poster

Sun Nov 15
8am–noon

Part of Session PSTR070: Effort, Choice, Social Reward, and Neuroeconomic Decision-Making

Characterizing the effects of GLP-1 agonists (semaglutide) on neuroeconomic decision-making behavior in a mouse model of binge eating disorder

WCC Halls A-C · Board HH25

Lecture

Sun Nov 15
noon–1pm

Part of Session LEC07: Clinical Neuroscience Lecture: Mending the Mind: From Single Neurons to Memory Neuroprosthetics

Moderator

WCC Hall D

Poster

Sun Nov 15
1–5pm

Part of Session LBP009: H.03. Motivation

Neuroeconomically dissociable decision-making computations are altered by Shank3 haploinsufficiency

WCC Halls A-C · Board B28

Poster

Sun Nov 15
1–5pm

Part of Session PSTR084: Transcription and Translation in Plasticity

Quinone reductase 2 reads H3 serotonylation to support neuronal maturation

WCC Halls A-C · Board L6

Poster

Sun Nov 15
1–5pm

Part of Session PSTR084: Transcription and Translation in Plasticity

Ketamine Induces a Sustained Increase in Histone H3 Serotonylation that Outlasts Its Acute Transcriptional Wave in the mPFC

WCC Halls A-C · Board L8

Poster

Sun Nov 15
1–5pm

Part of Session PSTR084: Transcription and Translation in Plasticity

The estrous cycle regulates histone serotonylation-associated gene expression patterns in the dorsal raphe nucleus

WCC Halls A-C · Board M2

Poster

Sun Nov 15
1–5pm

Part of Session PSTR084: Transcription and Translation in Plasticity

Histone serotonylation recruitment of KMT2E regulates chromatin dynamics in neurodevelopment

WCC Halls A-C · Board M3

Poster

Sun Nov 15
1–5pm

Part of Session PSTR093: Stroke Recovery: Mechanisms and Pharmacological Approaches

Targeting NETs Enhances Penumbra Reperfusion and Oxygenation After Ischemic Stroke in Aged Mice

WCC Halls A-C · Board V22

Poster

Sun Nov 15
1–5pm

Part of Session PSTR110: Neural Mechanisms of Human Social Cognition

Neurocomputational mechanisms of social norm learning in human prefrontal cortices

WCC Halls A-C · Board HH5

Poster

Sun Nov 15
1–5pm

Part of Session PSTR113: Genomic and Transcriptomic Techniques (Non-Human)

Single-chromatin fiber profiling links rDNA enhancer repeat variation to distinct epigenetic and transcriptional states in the mouse hippocampus

WCC Halls A-C · Board II24

Talk

Sun Nov 15
2–4:30pm

Part of Session MIN12: Embodied Computation: How Does Embodiment Impact Sensorimotor and Cognitive Processing

Chair

WCC Rm 151

Poster

Mon Nov 16
8am–noon

Part of Session PSTR124: Oligodendrocytes Development

Long-read Nanopore DNA sequencing reveals developmental and cell-type-specific DNA methylation and hydroxymethylation landscapes in human OPCs and oligodendrocytes

WCC Halls A-C · Board Q5

Poster

Mon Nov 16
8am–noon

Part of Session PSTR149: Mechanisms of Cocaine Use and Addiction

H2A.Z dysregulation during cocaine withdrawal modulates drug relapse behavior

WCC Halls A-C · Board GG8

Poster

Mon Nov 16
8am–noon

Part of Session PSTR151: Neural and Behavioral Mechanisms of Opioid Seeking, Withdrawal, and Relapse

Divergent transcriptional states distinguish high- and low-escalating oral oxycodone self-administration and persist into protracted abstinence

WCC Halls A-C · Board II6

Poster

Mon Nov 16
8am–noon

Part of Session PSTR152: Neural Substrates of Opioid Seeking

Multi-omic profiling of synthetic and non-synthetic opioid withdrawal reveals sex-specific epigenetic reprogramming of the nucleus accumbens

WCC Halls A-C · Board JJ10

Poster

Mon Nov 16
8am–noon

Part of Session PSTR155: Behavioral and Circuit Mechanisms of Social Behavior II

Stress reshapes social motivation through altered anterior cingulate cortex dynamics

WCC Halls A-C · Board KK35

Talk

Mon Nov 16
8:15–8:30am

Part of Session NANO19: Neural and Molecular Mechanisms of Addictive Drugs

Dopaminoceptive cells in the ventral hippocampus control cocaine action

WCC Rm 143

Session

Mon Nov 16
9–10am

Part of Session MTE06: Meet-the-Expert: Russo — Building a Translational Research Program to Study the Neuroimmune Mechanisms of Depression

Moderator

WCC Rm 201

Session

Mon Nov 16
10:30am–noon

Part of Session BTCR01: Overlap of GLP-1 Circuitry in Addiction and Obesity: Treatment Implications

Speaker

WCC Rm 152

Poster

Mon Nov 16
1–5pm

Part of Session PSTR194: Post-Traumatic Stress Disorder and Other Psychiatric Disorders: Human Studies and Therapeutic Approaches

Single-Nucleus Transcriptomic Profiling Reveals Disease- and Age-Associated Molecular Programs in the Human Ventral Midbrain

WCC Halls A-C · Board GG7

Poster

Mon Nov 16
1–5pm

Part of Session PSTR196: Pharmacological and Molecular Mechanisms in Substance Use Disorders

Effects of GLP-1R Deletion in Triangular Septal Nucleus Neurons on the Motivational Properties of Nicotine

WCC Halls A-C · Board HH8

Poster

Mon Nov 16
1–5pm

Part of Session PSTR204: Multi-Omics

Spatial Transcriptomic Niche Trajectories Reveal Coordinated Gene and Cell-Cell Communication Dynamics Across the Whole Mouse Brain

WCC Halls A-C · Board LL36

Talk

Mon Nov 16
3:45–4pm

Part of Session NANO25: Value, Memory, and Social Inference: Multi-Circuit Dynamics of Human Cognition

Shared neural dynamics underpin social belief inference

WCC Rm 143

Poster

Tue Nov 17
8am–noon

Part of Session LBP051: B.10. Neuro-Oncology

Plexin Receptors Control Coupling of Neuronal Activity to Glioblastoma Progression

WCC Halls A-C · Board C60

Poster

Tue Nov 17
8am–noon

Part of Session LBP051: B.10. Neuro-Oncology

KDM6B-mediated epigenetic-metabolic reprogramming shapes the immunosuppressive landscape in Glioblastoma

WCC Halls A-C · Board C61

Poster

Tue Nov 17
8am–noon

Part of Session PSTR216: Astrocytes: Signaling, Synaptic Regulation, and Circuit Function

Modulating astrocyte endfeet to increase blood-brain-barrier permeability

WCC Halls A-C · Board Q5

Poster

Tue Nov 17
8am–noon

Part of Session PSTR218: Brain Wellness and Aging

Investigating Microglial Plasticity and Function in Brain Aging

WCC Halls A-C · Board T11

Poster

Tue Nov 17
8am–noon

Part of Session PSTR218: Brain Wellness and Aging

Lifespan single-cell transcriptomic atlas of the human prefrontal cortex

WCC Halls A-C · Board T13

Poster

Tue Nov 17
8am–noon

Part of Session PSTR218: Brain Wellness and Aging

Single-molecule profiling of mitochondrial DNA accessibility in human and mouse brain

WCC Halls A-C · Board T15

Poster

Tue Nov 17
8am–noon

Part of Session PSTR218: Brain Wellness and Aging

Altered Cerebral White and Gray Matter Volumes during Aging and Vascular Disease in Great Apes

WCC Halls A-C · Board U4

Poster

Tue Nov 17
8am–noon

Part of Session PSTR219: Metabolic and Neural Changes Across Brain Aging: Experimental Models

WCC Halls A-C · Board U18

Poster

Tue Nov 17
8am–noon

Part of Session PSTR244: Cocaine: Reinforcement, Seeking, Reinstatement, and Memory

Effects of Chronic Cocaine Exposure on Approach/Avoidance Decision-Making

WCC Halls A-C · Board KK20

Poster

Tue Nov 17
8am–noon

Part of Session PSTR245: Clinical and Applied Mechanisms of Attention in Humans

Neural basis of improved sustained attention following sleep apnea treatment

WCC Halls A-C · Board KK56

Talk

Tue Nov 17
1–2:45pm

Part of Session NANO33: Neuronal Mechanisms of Misophonia

Chair

WCC Rm 140

Poster

Tue Nov 17
1–5pm

Part of Session PSTR284: Cocaine: Cell Signaling, Plasticity, Circuitry, and Glial Mechanisms

Synaptic neuroproteomic signatures of cocaine withdrawal across mesocorticolimbic brain regions

WCC Halls A-C · Board JJ16

Poster

Tue Nov 17
1–5pm

Part of Session PSTR284: Cocaine: Cell Signaling, Plasticity, Circuitry, and Glial Mechanisms

Sex- and Withdrawal-Dependent Remodeling of the Synaptic Proteome in the Nucleus Accumbens After Cocaine Exposure Reveals Ephexin1 as a Regulator of Cocaine Seeking

WCC Halls A-C · Board JJ17

Poster

Tue Nov 17
1–5pm

Part of Session PSTR284: Cocaine: Cell Signaling, Plasticity, Circuitry, and Glial Mechanisms

Circuit and transcriptomic mechanisms for dopamine receptor D2-expressing neurons in paraventricular nucleus of the thalamus: Role in cocaine-seeking behavior

WCC Halls A-C · Board KK4

Talk

Tue Nov 17
2:30–2:45pm

Part of Session NANO33: Neuronal Mechanisms of Misophonia

Impaired Reversal Learning in Misophonia: Behavioral and Neural Evidence from EEG

WCC Rm 140

Poster

Wed Nov 18
8am–noon

Part of Session LBP076: J.06. Computation, Modeling, and Simulation

Inferring neuromodulatory credit assignment in recurrent neural networks

WCC Halls A-C · Board C8

Talk

Wed Nov 18
8–11:15am

Part of Session NANO42: Sleep Systems in Health and Disease

Chair

WCC Rm 140

Poster

Wed Nov 18
8am–noon

Part of Session PSTR297: Animal Models of Autism

Neural basis of pharmacological amelioration of social deficits in Fmr1KO mice during juvenile sensitive period

WCC Halls A-C · Board D17

Poster

Wed Nov 18
8am–noon

Part of Session PSTR304: Alzheimer's Disease: Therapeutic Strategies: Amyloidosis Models

Effects of Intranasal VGF Derived TLQP-21 on Early- and Late-Stage Pathology in 5xFAD Model of Alzheimer's Disease

WCC Halls A-C · Board Web Only

Poster

Wed Nov 18
8am–noon

Part of Session PSTR307: Ataxias and Dystonia

Neurodegeneration and Inflammation in a Novel Spinocerebellar Ataxia 13 Preclinical Model

WCC Halls A-C · Board W24

Poster

Wed Nov 18
8am–noon

Part of Session PSTR321: Stress-Modulated Pathways: Anatomy, Physiology, Neurochemistry

Hormonal regulation of stress resilience through ERα-dependent plasticity mechanisms

WCC Halls A-C · Board FF23

Poster

Wed Nov 18
8am–noon

Part of Session PSTR324: Anxiety Disorders: Preclinical and Human Studies, Mechanisms, and Interventions

Neural Correlates of Day-to-Day Affective Variability: Frontopolar Involvement in Mood and Anxiety Disorders

WCC Halls A-C · Board II1

Talk

Wed Nov 18
10–10:15am

Part of Session NANO42: Sleep Systems in Health and Disease

Neocortical long-range inhibition promotes cortical synchrony and sleep

WCC Rm 140

Talk

Wed Nov 18
10:45–11:20am

Part of Session SYM14: Cross-Species Approaches to Understanding Human Cognition

Primate ventral frontal cortex contributions to decision-making

WCC Rm 151

Poster

Wed Nov 18
1–5pm

Part of Session LBP087: I.09. Spatial Navigation

The Earliest Signs of Cognitive Aging: Declining Precision, Stability, and Flexibility in Hippocampal Memory

WCC Halls A-C · Board C42

Poster

Wed Nov 18
1–5pm

Part of Session LBP088: I.10. Human Learning and Cognition

Social context shapes orbitofrontal responses to hippocampal sharp-wave ripples during human social navigation

WCC Halls A-C · Board C52

Poster

Wed Nov 18
1–5pm

Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States

Progression of medial entorhinal spatial coding deficits in a mouse model of temporal lobe epilepsy

WCC Halls A-C · Board N3

Poster

Wed Nov 18
1–5pm

Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States

Medial entorhinal layer 2 stellate cell activity is sufficient to drive type 2 dentate spikes and pathological hypersynchronous events in healthy and epileptic mice

WCC Halls A-C · Board N4

Poster

Wed Nov 18
1–5pm

Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States

Interneuron theta phase locking controls seizure susceptibility

WCC Halls A-C · Board N5

Poster

Wed Nov 18
1–5pm

Part of Session PSTR345: Seizure Networks, Circuit Dynamics, Detection, and Post-Seizure States

Circuit editing to boost long-range feedforward inhibition decreases chronic seizures in experimental temporal lobe epilepsy

WCC Halls A-C · Board N6

Poster

Wed Nov 18
1–5pm

Part of Session PSTR355: Viral and Infectious Mechanisms of Neuroinflammation II

Genetic dissection of acute and long-term anosmia following SARS-CoV-2 infection

WCC Halls A-C · Board X21

Poster

Wed Nov 18
1–5pm

Part of Session PSTR369: Sleep: Human Behavioral Studies

Time-on-task effects in sleep apnea patients on and off treatment

WCC Halls A-C · Board GG16

Poster

Wed Nov 18
1–5pm

Part of Session PSTR374: Neural Mechanisms of Stress and Depression in Animal Models

Single chromatin fiber and transcriptomic profiling of the 'postpartum' mouse brain

WCC Halls A-C · Board JJ8

Poster

Wed Nov 18
1–5pm

Part of Session PSTR380: Hippocampal Dynamics and Coding

Prior experience accelerates reward over-representation in novel environments to support learning-to-learn

WCC Halls A-C · Board LL28

Talk

Wed Nov 18
1:15–1:30pm

Part of Session NANO46: Molecular Physiology of Ligand-Gated Receptors and Ion Channels

Neurotransmission N-Glycosylation Profiles in Dorsolateral Prefrontal Cortex of Individuals with Major Depression and Bipolar Disorder

WCC Rm 140

Talk

Wed Nov 18
3:37–4pm

Part of Session MIN35: Paired Neuroimaging and Brain Omics From the Same Individuals for Disease Mechanisms and Diagnostics

Establishing the relationship between brain cellular senescence and brain structure

WCC Rm 147

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