University Medical Center Utrecht at ESGCT 2026

Oct 27–30, 2026 Hamburg, Germany ~2.5k attendees Website

University Medical Center Utrecht brings 8 presentations to ESGCT 2026 in Hamburg. Its work centres on base and prime editing in models of inherited metabolic, liver and lung disease, including primary ciliary dyskinesia and galactosemia. Other strands cover scalable in vivo editing of blood stem cells and market access for these therapies.

OrganizationESGCT 2026 Attendance
Hospitals & clinical centres
Dutch academic hospital whose regenerative medicine centre models genetic diseases with gene editing.
Talk
Wed Oct 28
9:45am–10:30am
NEO-AAV: an engineered extracellular vesicle-enveloped AAV platform for activation-coupled T cell transduction and CAR-T cell generation
SESSION 3a: AAVs/non integrative vectors II - Technology
Vectors and delivery (AAV, lentiviral, LNP)Cell therapies and CAR-T
Poster
Wed Oct 28
1:30pm–3:30pm
Precision adenine base editing of a pathogenic OTC variant in engineered hepatic models
Gene Editing
Talk
Thu Oct 29
9:50am–10:30am
Challenges in market access of GCTs
SESSION 7c: Accessibility of GT
Manufacturing, CMC and access
Poster
Thu Oct 29
2:00pm–4:00pm
Antibody-based targeted lysosomal degradation of circulating amyloidogenic immunoglobulin light chains as a novel therapeutic strategy for AL amyloidosis
Cardiovascular & Muscular diseases
Poster
Thu Oct 29
2:00pm–4:00pm
Less Is More: Defining healthy cell thresholds to restore mucociliary clearance in Primary Ciliary Dyskinesia
Disease Models
Rare and inherited disease
Poster
Thu Oct 29
2:00pm–4:00pm
Mismatched pegRNAs to inhibit self-complementarity of PBS and spacer for Classic Galactosemia
Gene Editing
Poster
Thu Oct 29
2:00pm–4:00pm
Toward scalable in vivo HSC genome editing for mevalonate kinase deficiency and beyond: a platform-based preclinical approach
Hematopoietic diseases & PID
Talk
Fri Oct 30
10:15am–10:30am
Back to the Bases: Scalable Modeling of Primary Ciliary Dyskinesia Variants with Base Editing
SESSION 11c: Disease models
Gene and epigenome editingRare and inherited disease

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