University College London at ESGCT 2026

Oct 27–30, 2026 Hamburg, Germany ~2.5k attendees Website

University College London brings 19 presentations to ESGCT 2026 in Hamburg. Its groups work on gene editing for inherited immune and metabolic disease and on non-viral delivery, including mRNA therapies for cystic fibrosis and primary ciliary dyskinesia. Further work covers AAV capsid design for muscular dystrophy and generating CAR T cells in the body.

OrganizationESGCT 2026 Attendance
Universities & institutes
London university with a large gene and cell therapy programme spanning AAV and lentiviral gene therapy, haemophilia and CAR-T trials.
Chair
Tue Oct 27
9:30am–11:00am
CLINICAL TRIALS AND COMMERCIALISATION WORKSHOP 1
with SR-Tiget
Manufacturing, CMC and accessClinical trials and translation
Workshop
Tue Oct 27
9:55am–10:45am
VLPs for in vivo CAR-T cells
EDUCATION SESSION 1b - Therapeutic strategies expanding the horizons of GT
Vectors and delivery (AAV, lentiviral, LNP)Cell therapies and CAR-T
Chair
Tue Oct 27
11:15am–1:00pm
CLINICAL TRIALS AND COMMERCIALISATION WORKSHOP 2
with SR-Tiget
Manufacturing, CMC and access
Chair
Wed Oct 28
8:30am–10:30am
SESSION 3b: Hematopoietic & PID
with Broad Institute
Rare and inherited disease
Talk
Wed Oct 28
9:30am–10:30am
Patient-specific gene editing approaches rescue B cell development in X-linked agammaglobulinemia
SESSION 3b: Hematopoietic & PID
Gene and epigenome editingRare and inherited disease
Chair
Wed Oct 28
11:00am–12:30pm
SESSION 4c: Immunotherapy and CAR T cells II
with IDIBAPS
Cell therapies and CAR-T
Poster
Wed Oct 28
1:30pm–3:30pm
BREAKING FREE FROM VIRUSES: TOWARD A SCALABLE NON-VIRAL PLATFORM FOR HSC GENE THERAPY
Non viral delivery
Poster
Wed Oct 28
1:30pm–3:30pm
Combinatorial CRISPR-activation Gene Therapy to Treat Intractable Epilepsy
CNS & sensory
Poster
Wed Oct 28
1:30pm–3:30pm
Developing a 3D in vitro model of skeletal muscle involvement in late-onset Pompe disease for CRISPR-based therapy testing
Cardiovascular & Muscular diseases
Poster
Wed Oct 28
1:30pm–3:30pm
Development of in vitro transcribed mRNA therapeutics for cystic fibrosis combined with CFTR modulators.
Non viral delivery
Poster
Wed Oct 28
1:30pm–3:30pm
Improving the gene therapy vector and applying lipidomics to monitor the efficacy of therapy for CLN3 disease.
AAVs / non integrative vectors
Poster
Wed Oct 28
1:30pm–3:30pm
Restoration of cilia motility via mRNA therapy in Primary Ciliary Dyskinesia
Non viral delivery
Poster
Wed Oct 28
1:30pm–3:30pm
The Development of a PEG-bPEI Nanogel-based Delivery System for Nucleic Acids
Non viral delivery
Chair
Wed Oct 28
6:00pm–7:00pm
SESSION 6: Gene editing
with CIEMAT
Gene and epigenome editing
Chair
Thu Oct 29
8:30am–10:30am
SESSION 7c: Accessibility of GT
with SR-Tiget
Manufacturing, CMC and access
Talk
Thu Oct 29
8:30am–10:30am
SESSION 7d: Skin, pulmonary and skeletal diseases
SESSION 7d: Skin, pulmonary and skeletal diseases
Rare and inherited disease
Talk
Thu Oct 29
12:30pm–1:00pm
Prime Time for patients with metabolic diseases
SESSION 8: Presidential Symposium
Gene and epigenome editingRare and inherited disease
Poster
Thu Oct 29
2:00pm–4:00pm
A two-in-one AAV donor strategy for manufacturing IMiD-switchable anti-B7H3 CAR T cells
Immunotherapy and CAR T cells
Poster
Thu Oct 29
2:00pm–4:00pm
Cleavage-competent sgRNA contaminants and enhanced off-target detection revealed by DNA repair inhibition in genome-edited HSPCs
Gene Editing
Poster
Thu Oct 29
2:00pm–4:00pm
Cryo-EM analysis of viral vector heterogeneity
Manufacturing
Poster
Thu Oct 29
2:00pm–4:00pm
Mutation, exon or gene; Trade-offs between correction and cell function for different scales of non-viral HDRT ex vivo correction of XLA.
Gene Editing
Poster
Thu Oct 29
2:00pm–4:00pm
Rational design AAV capsid engineering for fibroblast-directed targeting towards Collagen VI muscular dystrophy genetic therapies.
AAVs / non integrative vectors
Chair
Fri Oct 30
9:00am–10:30am
SESSION 11b: Bleeding disorders
with SR-Tiget
Rare and inherited disease
Talk
Fri Oct 30
9:10am–10:30am
Gene therapy in hemophilia
SESSION 11b: Bleeding disorders
Rare and inherited diseaseClinical trials and translation
Talk
Fri Oct 30
12:00pm–1:00pm
A human multi-organoid framework to improve preclinical assessment of AAV gene therapy in neuromuscular disease
SESSION 12a: AAVs/non integrative vectors III - Translation
Vectors and delivery (AAV, lentiviral, LNP)Rare and inherited disease
Talk
Fri Oct 30
12:15pm–1:00pm
Targeted lipid nanocomplex delivery of angiopoietin-1 mRNA slows progression of childhood kidney disease
SESSION 12d: Non-viral vectors/Nanotechnology and RNA therapeutics II
Vectors and delivery (AAV, lentiviral, LNP)RNA and oligonucleotide therapies

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