Nantes Université at ESGCT 2026

Oct 27–30, 2026 Hamburg, Germany ~2.5k attendees Website

Nantes Université brings 9 presentations to ESGCT 2026 in Hamburg. Its work covers AAV gene therapy for neuromuscular and retinal disease, including a proof of concept for Stargardt disease. Other strands study immune responses to AAV in the liver and the production and titration methods behind clinical-grade vectors.

OrganizationESGCT 2026 Attendance
Nantes Université
Nantes, France
Universities & institutes
French university whose TaRGeT lab, run with Inserm, develops AAV gene therapies for neuromuscular and retinal diseases.
Poster
Wed Oct 28
1:30pm–3:30pm
Adoptive transfer of pre-existing anti-AAV human T cells leads to deleterious immune response in the liver of a preclinical humanized mouse model.
Immune responses to GT
Poster
Wed Oct 28
1:30pm–3:30pm
Analytical development and performance evaluation of ITR-targeted digital PCR method for AAV vector titration
AAVs / non integrative vectors
Poster
Wed Oct 28
1:30pm–3:30pm
Beyond Rodents: A Laser-Induced Yucatan Minipig Model of Age-Related Macular Degeneration for Gene and Cell Therapy Evaluation
Disease Models
Poster
Wed Oct 28
1:30pm–3:30pm
Towards Cost-Independent rAAV Manufacturing: Proprietary Suspension-Adapted HEK293 Sub-Clones Deliver Competitive Productivity and Vector Quality Across Clinically Relevant Transgenes and Serotypes
Manufacturing
Poster
Wed Oct 28
1:30pm–3:30pm
Translation of Recombinant AAV Production from 2D to 4D Bioprocess Adherent Platform
Manufacturing
Poster
Wed Oct 28
1:30pm–3:30pm
Validation of adeno-associated viral vector inactivation by chemical processes
AAVs / non integrative vectors
Chair
Thu Oct 29
8:30am–10:30am
SESSION 7a: Immune responses to GT
with Nava Therapeutics
Vectors and delivery (AAV, lentiviral, LNP)Clinical trials and translation
Poster
Thu Oct 29
2:00pm–4:00pm
Chemical carbohydrate engineering of AAV capsids reveals receptor-mediated OFF/ON control of gene transfer efficiency.
AAVs / non integrative vectors
Poster
Thu Oct 29
2:00pm–4:00pm
In vitro and in vivo AAV tropism within the enteric nervous system
AAVs / non integrative vectors
Poster
Thu Oct 29
2:00pm–4:00pm
Stargardt Therapeutic ABCA4 Restoration: proof-of- concept for the ABCA4 gene and Stargardt disease
Gene Editing

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