KU Leuven at ESGCT 2026

Oct 27–30, 2026 Hamburg, Germany ~2.5k attendees Website

KU Leuven brings 8 presentations to ESGCT 2026 in Hamburg. Its work covers AAV production and purification, including separating full from empty capsids and reference materials for standardisation. A second strand uses prime and precision editing in models of cystic fibrosis and the kidney disease cystinosis.

OrganizationESGCT 2026 Attendance
KU Leuven
Leuven, Belgium
Universities & institutes
Belgian research university with gene therapy groups working on AAV and lentiviral vectors.
Poster
Wed Oct 28
1:30pm–3:30pm
Improved AAV9 capsid quality and productivity using the pPLUS® AAV plasmid platform and DoE-based optimization
Manufacturing
Poster
Wed Oct 28
1:30pm–3:30pm
Omics-to-optimization: enhancing recombinant AAV vector production via innate immune pathway modulation
Manufacturing
Poster
Wed Oct 28
1:30pm–3:30pm
One-step flow-through membrane chromatography for enrichment of full Adeno-associated viral vector capsids through selective empty capsid retention
AAVs / non integrative vectors
Poster
Thu Oct 29
2:00pm–4:00pm
An expanded isogenic model of cystinosis myopathy reveals progressive impairment of myogenesis and rescue by CTNS re-expression
Lentiviral vectors / Integrative vectors
Poster
Thu Oct 29
2:00pm–4:00pm
Development of an AAV9 Full, Partially filled, and Empty Reference Standard material to promote standardisation of capsid content characterisation.
AAVs / non integrative vectors
Poster
Thu Oct 29
2:00pm–4:00pm
Human Myoblasts/hiPSCs Derived Skeletal Muscle Models to Investigate Cystinosis Myopathy
Disease Models
Rare and inherited disease
Poster
Thu Oct 29
2:00pm–4:00pm
Precise correction of challenging mutations causing cystic fibrosis through transient delivery of the prime editing machinery
Gene Editing
Poster
Thu Oct 29
2:00pm–4:00pm
Precision gene editing to generate and correct in vitro the most common nonsense mutation in cystinosis
Gene Editing
Chair
Fri Oct 30
11:00am–1:00pm
SESSION 12a: AAVs/non integrative vectors III - Translation
with Broad Institute
Vectors and delivery (AAV, lentiviral, LNP)Clinical trials and translation

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