Dyno Therapeutics at ESGCT 2026
Oct 27–30, 2026 Hamburg, Germany ~2.5k attendees Website
Dyno Therapeutics brings 3 presentations to ESGCT 2026 in Hamburg. Its work centres on machine learning design of AAV capsids that reach the brain and muscle after dosing into the bloodstream. The capsids shown include one targeting ALPL across species, one tuned for muscle over brain, and variants that evade existing antibodies.
| Organization | ESGCT 2026 Attendance |
|---|---|
Dyno Therapeutics Watertown, Massachusetts | |
Uses AI to design AAV capsids with better delivery to tissues such as the brain and muscle, and partners with gene therapy developers. | Poster Wed Oct 28 1:30pm–3:30pm AI-enabled single-shot design of an ALPL-targeting AAV capsid with exceptional cross-species CNS and muscular delivery efficiency following systemic administration Poster Thu Oct 29 2:00pm–4:00pm AI-guided engineering of dual-mechanism AAV capsids enhances muscle delivery, reduces CNS tropism, and confers cross-species translation in NHP and mouse Poster Thu Oct 29 2:00pm–4:00pm Systematic iterative AI-enabled engineering of antibody-evasive AAV capsids across diverse CNS- and muscle-targeting mechanisms |
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