Charité – Universitätsmedizin Berlin at ESGCT 2026

Oct 27–30, 2026 Hamburg, Germany ~2.5k attendees Website

Charité – Universitätsmedizin Berlin brings 15 presentations to ESGCT 2026 in Hamburg. Its work centres on engineered T cells and regulatory T cells for cancer and transplantation, and on manufacturing them without viral vectors. One strand uses base editing to make those cells resistant to the immunosuppressive drugs patients take alongside the therapy.

OrganizationESGCT 2026 Attendance
Hospitals & clinical centres
Berlin's university hospital and medical faculty, with research and trials in cell and gene therapy, including engineered T cells.
Talk
Tue Oct 27
6:00pm–7:30pm
Adenine base editing of FKBP12 and NR3C1 creates tacrolimus- and glucocorticoid-resistant T cells and Tregs for transplant immunotherapy
SESSION 2b: (Epi)genome editing I
Gene and epigenome editingCell therapies and CAR-T
Poster
Wed Oct 28
1:30pm–3:30pm
Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation
Immunotherapy and CAR T cells
Poster
Wed Oct 28
1:30pm–3:30pm
Computational structure prediction guides rational design of enhanced CARs targeting a membrane-proximal epitope of IgA1
Immunotherapy and CAR T cells
Poster
Wed Oct 28
1:30pm–3:30pm
Lipid nanoparticle-mediated multiplex engineering for virus free and scalable ex vivo manufacturing of T cells
Gene Editing
Poster
Wed Oct 28
1:30pm–3:30pm
Modulated CD3z signaling enhances persistence and tumor control of non-viral TRAC-integrated FcRL5-CAR T cells for MM and CLL
Immunotherapy and CAR T cells
Poster
Wed Oct 28
1:30pm–3:30pm
Multidimensional Evaluation of TCE-09B, a Novel Serum-Free Medium for Non-Viral CAR-T Cell Manufacturing
Immunotherapy and CAR T cells
Poster
Wed Oct 28
1:30pm–3:30pm
Scalable GMP-compliant manufacturing of T-cell products using semi-closed and automated bioreactors
Manufacturing
Poster
Wed Oct 28
1:30pm–3:30pm
Toward Off-the-Shelf Treg Therapies: Integrating Immunogenicity Prediction and Functional Validation Platforms
Disease Models
Cell therapies and CAR-T
Poster
Thu Oct 29
2:00pm–4:00pm
Combinatorial CD4+ and CD8+ TCR-T Cell therapy enhances anti-tumor responses to mutant p53
Immunotherapy and CAR T cells
Poster
Thu Oct 29
2:00pm–4:00pm
Development and Comprehensive Characterization of GMP-Compliant Effector T Cells for Advanced Adoptive T-Cell Therapy
Immunotherapy and CAR T cells
Poster
Thu Oct 29
2:00pm–4:00pm
Establishment of a PTLD infection model and functional analysis of EBV-specific T-cells
Immunotherapy and CAR T cells
Poster
Thu Oct 29
2:00pm–4:00pm
Multiplex gene-edited "off the shelf" CAR T cells resist allo-rejection and glucocorticoid co-treatment
Immunotherapy and CAR T cells
Poster
Thu Oct 29
2:00pm–4:00pm
Optimizing Functional Assays for the Evaluation of regulatory T Cell product candidates
Disease Models
Cell therapies and CAR-T
Poster
Thu Oct 29
2:00pm–4:00pm
Pooled knock-in screening reveals principles for improved CAR T-cell design
Immunotherapy and CAR T cells
Talk
Fri Oct 30
12:30pm–1:00pm
One-pot PASTA: A CRISPR-integrase platform for efficient, site-specific integration of large transgenes in primary human T cells
SESSION 12b: Genome Editing III
Gene and epigenome editingCell therapies and CAR-T

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