Upstream processing and cell culture at BPI West 2027
Mar 16–18, 2027 San Diego, CA ~800 attendees Website
14 organizations at BPI West 2027 present work in upstream & cell culture: 11 drug developers, 2 academic, government and non-profit bodies and 1 supplier or service provider. Between them they bring 57 presentations to the program. Most represented: Sanofi (8 on the program), AstraZeneca (7 on the program), Regeneron (7 on the program). As of Oct 15, 2026.
Format
Top represented
Showing 1–8 of 14 organizations
| Organization | BPI West 2027 Attendance |
|---|---|
Sanofi Paris, France | |
Global pharmaceutical company developing and manufacturing biologics, vaccines and genomic medicines. | Talk Tue Mar 16 10:00am–10:30am Talk Tue Mar 16 11:30am–12:00pm Talk Wed Mar 17 11:15am–11:45am Talk Wed Mar 17 4:15pm–4:45pm Cell Culture Digital Twins for Improving Process Scale-Up How digital twins, computer models that mirror a cell culture process, help move it from lab to factory scale with consistent results. Talk Thu Mar 18 9:00am–9:30am Talk Thu Mar 18 9:00am–9:30am Talk Thu Mar 18 2:30pm–3:00pm Also |
AstraZeneca Cambridge, United Kingdom | |
Global pharmaceutical company developing and manufacturing biologics, including antibodies and antibody-drug conjugates. | Talk Tue Mar 16 9:00am–9:30am Live Digital Twins and Agentic AI Enable Titer Prediction and Early Error Detection: Towards Self-Driving Biomanufacturing How live computer models predict product levels in bioreactors with steady medium flow and warn 8 to 24 hours before filters clog. Talk Tue Mar 16 9:00am–9:30am Talk Wed Mar 17 2:00pm–2:30pm Accelerating Cell Line Development: Saving Time and Increasing Capacity Ways to speed up cell line development, the hunt for cells that make a drug well, and fit more projects through it. Talk Wed Mar 17 2:30pm–3:00pm Engineering Automated Sampling, Purification, and Analytical Methods to Facilitate Online Product Quality Monitoring to Support Bioprocess Development How an automated, sterile sampler drawing from 8 bioreactors lets chromatography track protein drug quality, such as clumping, almost in real time. Talk Wed Mar 17 4:45pm–5:15pm Mechanistic Modeling for Decision-Based Bioreactor Scale-Up How physics-based models of oxygen use and carbon dioxide buildup guided air bubbling and antifoam choices when scaling cell culture to manufacturing. Talk Thu Mar 18 2:00pm–2:30pm Beyond Ex Vivo CAR-T: Designing Lentiviral Vector Manufacturing for In Vivo Cell Therapy Why lentiviral vectors dosed straight into patients for cell therapy inside the body need new manufacturing standards beyond those built for lab-made CAR-T. Talk Thu Mar 18 2:00pm–2:30pm |
Regeneron Tarrytown, New York | |
Biopharmaceutical company with marketed antibody medicines and in-house biologics, gene therapy and cell therapy process development and manufacturing. | Talk Wed Mar 17 11:45am–12:15pm A High-Throughput Approach to Virus Retentive Filtration Process Development and Characterization How testing virus-removal filters under many conditions at once, varying pH, additives and protein levels, speeds development of this purification step. Talk Thu Mar 18 11:15am–11:45am Talk Thu Mar 18 11:15am–11:45am Talk Thu Mar 18 11:45am–12:15pm Talk Thu Mar 18 2:00pm–2:30pm Talk Thu Mar 18 2:30pm–3:00pm |
Alexion Boston, Massachusetts | |
AstraZeneca's rare disease business, developing and manufacturing biologics for rare conditions. | Talk Wed Mar 17 10:00am–10:30am Talk Wed Mar 17 11:15am–11:45am Talk Wed Mar 17 2:00pm–2:30pm Talk Wed Mar 17 2:00pm–2:30pm Talk Wed Mar 17 2:30pm–3:00pm Rapid Screening to Compare Process Conditions and Identify Low-Risk Conditions for PS80 Degradation in Downstream Process Development How a fast fatty acid test screens purification conditions early for ones that spare polysorbate 80, a detergent added to protein drugs. Also |
Amgen Thousand Oaks, California | |
Global biopharmaceutical company developing and manufacturing biologic medicines. | Talk Tue Mar 16 9:00am–9:30am Keynote Tue Mar 16 2:35pm–3:20pm Speed Without Shortcuts: How AI is Transforming CMC and Validation at Amgen CMC, Digital & Manufacturing Strategy Talk Wed Mar 17 9:30am–10:00am Talk Wed Mar 17 11:45am–12:15pm Talk Thu Mar 18 9:00am–9:30am Also |
Bayer Leverkusen, Germany | |
Global pharmaceutical company with cell and gene therapy programs alongside its marketed medicines. | Talk Wed Mar 17 9:30am–10:00am Talk Wed Mar 17 10:00am–10:30am Product Development of a Phase III (and Beyond) Parkinson’s Allogeneic Cell Therapy using Process and Analytic Platforms How automated 2D and 3D culture platforms aim to make dopamine neurons for Parkinson's as an off-the-shelf therapy, cheaper and at scale. Talk Thu Mar 18 9:00am–9:30am Talk Thu Mar 18 9:00am–9:30am Implementing a Lower-Cost Resin in a Licensed Process: A CMC Case Study How an approved drug's purification switched to a cheaper chromatography resin, with small-scale tests showing the product unchanged through commercial validation. Talk Thu Mar 18 4:15pm–4:45pm |
Novartis Basel, Switzerland | |
Global pharmaceutical company developing and manufacturing biologics and cell and gene therapies; also offers contract manufacturing capacity. | Talk Wed Mar 17 9:00am–9:30am Talk Wed Mar 17 11:45am–12:15pm Talk Thu Mar 18 2:00pm–2:30pm Talk Thu Mar 18 4:45pm–5:15pm |
Astellas Tokyo, Japan | |
Pharmaceutical company with marketed medicines in oncology, urology and other areas, plus cell and gene therapy programs. | Talk Thu Mar 18 11:45am–12:15pm Talk Thu Mar 18 11:45am–12:15pm Shared Session: AAV upstream Development Through an Automated, High-Throughput Ambr250 Scale- Down Platform How a 2-liter process for making adeno-associated virus was scaled down, with automated transfection, to run more experiments using less material and labor. Talk Thu Mar 18 2:00pm–2:30pm Accelerating RPE Electroporation Optimization Through Design of Experiments How statistically planned experiments tuned electroporation, using electric pulses to deliver genes into cells, 5 times faster with 78% lower material costs. |
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