University of Bristol at ASHG 2026

Oct 20–24, 2026 Montréal, Canada ~7.5k attendees Website

University of Bristol brings 9 presentations from 6 research groups to ASHG 2026 in Montréal. Its program centres on population genetics, computational analysis and therapeutic research, with reproductive and prenatal genetics also represented. MRC Integrative Epidemiology Unit examines gut microbiome causality and pregnancy safety of antibody treatments, Diverse Epigenetic Epidemiology Partnership (DEEP) compares methylation across ancestries, and DMER Group studies gene and protein regulation.

Organization	ASHG 2026 Attendance
University of Bristol Bristol, UK	4 PhD Students · 2 PIs · 1 Postdoc · 1 Faculty
MRC Integrative Epidemiology Unitbristol.ac.uk/integrative-epidemiology Dry lab~37 people Analyzes GWAS, DNA methylation, metabolomic, proteomic and electronic health-record data with Mendelian randomization and machine learning. Studies causal drivers of chronic disease and pregnancy complications. 184 papers since 2024 › Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality JAMA, 2024 Epigenetic Aging and Racialized, Economic, and Environmental Injustice JAMA Network Open, 2024 Non-linear Mendelian randomization: detection of biases using negative controls with a focus on BMI, Vitamin D and LDL cholesterol European Journal of Epidemiology, 2024 Source: OpenAlex author A5013184354 Funded by Medical Research Council (MRC), part of UKRI › Medical Research Council (MRC), part of UKRI, MRC IEU core funding · began in April 2023; five years “The new funding, from the Medical Research Council, part of UKRI, totals £11,637,000.” Source: lab pages 12 platforms and techniques › Analyzes GWAS summary datasets, mQTL database, Genome-wide SNP data, Metabolomic data, Proteomic data, Electronic health records Techniques Mendelian randomization, Genetic colocalization, Target trial emulation, Machine learning, Literature mining, LD score regression Source: lab pages Currently hiring › “The MRC Integrative Epidemiology Unit recruits and supports staff and PhD students from multiple disciplines” Source: lab positions page	Poster Wed Oct 21 2:30 pm Part of Statistical Genetics and Genetic Epidemiology Poster Wednesday Session Assessing the causal role of the gut microbiome in human health and disease: a systematic review and application of Mendelian randomization in cancer aetiology Exhibit & Poster Hall · Board 8368W Collaborators: Pennington Biomedical Research Center Mendelian randomizationMicrobiomeCancerGenetic epidemiology Poster Wed Oct 21 2:30 pm ★ Reviewers’ Choice Part of Statistical Genetics and Genetic Epidemiology Poster Wednesday Session Evaluating the consequences of childhood adiposity on the human plasma proteome at four timepoints across the lifecourse Exhibit & Poster Hall · Board 8399W Collaborators: The University of Queensland, Shenzhen Bay Laboratory +1 more Genetic epidemiologyMendelian randomizationObesityProteomics Poster Fri Oct 23 2:30 pm Part of Prenatal, Perinatal, Reproductive, and Developmental Genetics Poster Friday Session Investigating the safety profile of monoclonal antibody therapeutics during pregnancy: a drug target Mendelian randomization study dissecting maternal and fetal genetic effects Exhibit & Poster Hall · Board 3020F Mendelian randomizationTeratogensPharmacologic therapyAutoimmune disorder
Diverse Epigenetic Epidemiology Partnership (DEEP)deep-epigenetics.org Wet + dry lab Generates and analyzes Illumina methylation and genetic array data. Studies disease mechanisms and risk prediction across ancestries, focusing on child and cardiovascular health. Funded by Medical Research Council, United Kingdom › Medical Research Council, United Kingdom · active “This 5-year project is funded by the Medical Research Council in the United Kingdom.” Source: lab pages 10 platforms and techniques › Runs Illumina H3A, Illumina Asian Screening Array, Illumina EPIC2, H3Africa BeadChip, Illumina EPIC BeadChip Techniques Epigenome-wide association studies, mQTL analysis, Ancestry and local-ancestry analysis, Disease and exposure prediction, Advanced statistical analyses Source: lab pages No openings posted	Poster Fri Oct 23 2:30 pm Part of Genetic, Genomic, and Epigenomic Resources and Databases Poster Friday Session Understanding disease discordance across ancestries through federated analysis of DNA methylation variation in the Diverse Epigenetic Epidemiology Partnership (DEEP) consortium Exhibit & Poster Hall · Board 4056F Collaborators: London School of Hygiene & Tropical Medicine, Academy of Scientific and Innovative Research EpigeneticsGenetic epidemiologyEpigenome-wide association studiesMethylation
DMER Groupbiocompute.org.uk Dry lab~19 people Integrates biomedical and epidemiological data with EpiGraphDB, OpenGWAS and BERT. Uses Mendelian randomization, knowledge graphs and EHR data for disease mechanisms and drug-target prioritization. 94 papers since 2024 › Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions Molecular Psychiatry, 2025 The effect of SGLT2 inhibition on prostate cancer: Mendelian randomization and observational analysis using electronic healthcare and cohort data Cell Reports Medicine, 2024 Transcriptome-wide Mendelian randomization during CD4+ T cell activation reveals immune-related drug targets for cardiometabolic diseases Nature Communications, 2024 Source: OpenAlex author A5036589831 Funded by UK Medical Research Council, World Cancer Research Fund › UK Medical Research Council, MRC Integrative Epidemiology Unit · active “funded by the UK Medical Research Council as part of the MRC Integrative Epidemiology Unit” World Cancer Research Fund · active “In work funded by the World Cancer Research Fund” Source: lab pages 12 platforms and techniques › Analyzes EpiGraphDB, OpenGWAS, MR-Base, ASQ, MendelVar, CScape, FATHMM Techniques Knowledge graphs, Language models, Mendelian randomization and genetic colocalization, Target trial emulation, Cross-ancestry proteome-wide MR Source: lab pages No openings posted	Poster Fri Oct 23 2:30 pm Part of Statistical Genetics and Genetic Epidemiology Poster Friday Session Evaluating discordance between expression quantitative trait loci and protein quantitative trait loci using enrichment analysis Exhibit & Poster Hall · Board 8391F Expression quantitative trait lociQuantitative traitEpidemiologyGenetic epidemiology
Immunopsychiatry: Inflammation and Psychiatry Research Groupimmunopsychiatry.com/team Wet + dry lab~16 people Studies inflammation in psychiatric disorders using population cohorts, genetic analyses, proteomics and early-phase clinical trials. Targets causal mechanisms and treatments for depression and schizophrenia. 60 papers since 2024 › Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study Translational Psychiatry, 2025 Immuno-metabolic depression: from concept to implementation The Lancet Regional Health - Europe, 2024 A novel biomarker of interleukin 6 activity and clinical and cognitive outcomes in depression Psychoneuroendocrinology, 2024 Source: OpenAlex author A5015663073 Funded by Wellcome Trust, MRC +9 more › MRC, Immunopsychiatry Programme · active “Funded by the MRC, we are examining:” MRC, Psychosis Immune Mechanism Stratified Medicine · active “Funded by the MRC and supported by the NIHR Bristol BRC” NIHR Bristol BRC, Psychosis Immune Mechanism Stratified Medicine · active “Funded by the MRC and supported by the NIHR Bristol BRC” +8 more on the lab page Source: lab pages 8 platforms and techniques › Techniques Mendelian randomization, genetic colocalization, trajectory based modelling, machine learning, polygenic risk score, causal inference, multi-omics, immunotherapy clinical trials Source: lab pages Currently hiring › “Golam is pleased to consider applications from prospective PhD students, staff and interns.” Source: lab positions page	Poster Thu Oct 22 4:15 pm Part of Complex Traits and Polygenic Disorders Poster Thursday Session Relationship between IL6 activity, inflammatory markers and psychiatric conditions: findings from UK Biobank cohort and genetic analyses Exhibit & Poster Hall · Board 8305T Collaborators: Norwegian Institute of Public Health, NIHR Bristol Biomedical Research Centre +1 more DepressionGenome-wide association studyImmune systemProteomics
Lifecourse GWAS Consortiumlifecourse-gwas.github.io Dry lab~15 people Analyzes genome-wide association results from 50 cohort studies and biobanks, stratified by age, sex and ancestry. Builds polygenic risk scores and Mendelian-randomisation instruments across age. 17 papers since 2024 › A structural mean modeling Mendelian randomization approach to investigate the lifecourse effect of adiposity: applied and methodological considerations American Journal of Epidemiology, 2025 The role of body image dissatisfaction in the relationship between body size and disordered eating and self-harm: complimentary Mendelian randomization and mediation analyses Molecular Psychiatry, 2024 A Qualitative Analysis of the Perceptions of Stakeholders Involved in Vector Control and Vector-Borne Disease Research and Surveillance in Orinoquia, Colombia Tropical Medicine and Infectious Disease, 2024 Source: OpenAlex author A5047148652 4 platforms and techniques › Techniques Genome-wide association studies, Mendelian randomisation, Polygenic risk scores, Cross-cohort harmonisation Source: lab pages No funding stated · No openings posted	Poster Fri Oct 23 2:30 pm Part of Statistical Genetics and Genetic Epidemiology Poster Friday Session Genetic effects on complex traits exhibit distinct patterning across the lifecourse Exhibit & Poster Hall · Board 8396F Collaborators: The University of Queensland, University of Bergen +5 more Complex traitsGenetic epidemiologyGenome-wide association studyMethodology
Skin Genetics Consortiumskingeneticsconsortium.org Dry lab~59 people Analyzes population-scale genomic data from biobanks and electronic health records to study skin diseases and traits. Shares results through the Skin Knowledge Portal. Funded by Leo Foundation › Leo Foundation · active “This initial project is funded by the Leo Foundation.” Source: lab pages 3 platforms and techniques › Techniques GWAS, Mendelian randomization, EHR phenotype genetic analysis Source: lab pages No openings posted	Poster Wed Oct 21 2:30 pm ★ Reviewers’ Choice Part of Statistical Genetics and Genetic Epidemiology Poster Wednesday Session Utilizing the Genotype-Phenotype Map (GPMap) to uncover shared skin biology and prioritize drug targets Exhibit & Poster Hall · Board 8472W Complex diseasesComputational toolsGenetic epidemiologyGenome-wide association study
1 more presenter — research group not yet identified

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