ASHG 2026 · Tier 2–3 Academic

University of Bristol at ASHG 2026

Bristol, UK

University of Bristol at ASHG 2026 in Montréal: 9 presentations (9 posters); 6 research groups.

9
presentations on the program
6
research groups identified
2
Reviewers’ Choice abstracts

Explore everyone at ASHG 2026 →

OrganizationASHG 2026 Attendance
University of Bristol
Bristol, UK
4 PhD Students · 2 PIs · 1 Postdoc · 1 Faculty
MRC Integrative Epidemiology Unitbristol.ac.uk/integrative-epidemiology
Dry lab~37 people
Analyzes GWAS, DNA methylation, metabolomic, proteomic and electronic health-record data with Mendelian randomization and machine learning. Studies causal drivers of chronic disease and pregnancy complications.
184 papers since 2024
Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality
JAMA, 2024
Epigenetic Aging and Racialized, Economic, and Environmental Injustice
JAMA Network Open, 2024
Non-linear Mendelian randomization: detection of biases using negative controls with a focus on BMI, Vitamin D and LDL cholesterol
European Journal of Epidemiology, 2024
Source: OpenAlex author A5013184354
Funded by Medical Research Council (MRC), part of UKRI
Medical Research Council (MRC), part of UKRI, MRC IEU core funding · began in April 2023; five years
“The new funding, from the Medical Research Council, part of UKRI, totals £11,637,000.”
Source: lab pages
12 platforms and techniques
Analyzes
GWAS summary datasets, mQTL database, Genome-wide SNP data, Metabolomic data, Proteomic data, Electronic health records
Techniques
Mendelian randomization, Genetic colocalization, Target trial emulation, Machine learning, Literature mining, LD score regression
Source: lab pages
Currently hiring
“The MRC Integrative Epidemiology Unit recruits and supports staff and PhD students from multiple disciplines”
Source: lab positions page
Poster
Wed Oct 21
2:30 pm
Assessing the causal role of the gut microbiome in human health and disease: a systematic review and application of Mendelian randomization in cancer aetiology
Statistical Genetics and Genetic Epidemiology
Collaborators: Pennington Biomedical Research Center
Mendelian randomizationMicrobiomeCancerGenetic epidemiology
Poster
Wed Oct 21
2:30 pm
★ Reviewers’ Choice
Evaluating the consequences of childhood adiposity on the human plasma proteome at four timepoints across the lifecourse
Statistical Genetics and Genetic Epidemiology
Collaborators: The University of Queensland, Shenzhen Bay Laboratory +2 more
Genetic epidemiologyMendelian randomizationObesityProteomics
Poster
Fri Oct 23
2:30 pm
Investigating the safety profile of monoclonal antibody therapeutics during pregnancy: a drug target Mendelian randomization study dissecting maternal and fetal genetic effects
Prenatal, Perinatal, Reproductive, and Developmental Genetics
Mendelian randomizationTeratogensPharmacologic therapyAutoimmune disorder
Diverse Epigenetic Epidemiology Partnership (DEEP)deep-epigenetics.org
Wet + dry lab
Generates and analyzes Illumina methylation and genetic array data. Studies disease mechanisms and risk prediction across ancestries, focusing on child and cardiovascular health.
Funded by Medical Research Council, United Kingdom
Medical Research Council, United Kingdom · active
“This 5-year project is funded by the Medical Research Council in the United Kingdom.”
Source: lab pages
10 platforms and techniques
Runs
Illumina H3A, Illumina Asian Screening Array, Illumina EPIC2, H3Africa BeadChip, Illumina EPIC BeadChip
Techniques
Epigenome-wide association studies, mQTL analysis, Ancestry and local-ancestry analysis, Disease and exposure prediction, Advanced statistical analyses
Source: lab pages
No openings posted
Poster
Fri Oct 23
2:30 pm
Understanding disease discordance across ancestries through federated analysis of DNA methylation variation in the Diverse Epigenetic Epidemiology Partnership (DEEP) consortium
Genetic, Genomic, and Epigenomic Resources and Databases
Collaborators: London School of Hygiene & Tropical Medicine, Academy of Scientific and Innovative Research
EpigeneticsGenetic epidemiologyEpigenome-wide association studiesMethylation
DMER Groupbiocompute.org.uk
Dry lab~19 people
Integrates biomedical and epidemiological data with EpiGraphDB, OpenGWAS and BERT. Uses Mendelian randomization, knowledge graphs and EHR data for disease mechanisms and drug-target prioritization.
94 papers since 2024
Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions
Molecular Psychiatry, 2025
The effect of SGLT2 inhibition on prostate cancer: Mendelian randomization and observational analysis using electronic healthcare and cohort data
Cell Reports Medicine, 2024
Transcriptome-wide Mendelian randomization during CD4+ T cell activation reveals immune-related drug targets for cardiometabolic diseases
Nature Communications, 2024
Source: OpenAlex author A5036589831
Funded by UK Medical Research Council, World Cancer Research Fund
UK Medical Research Council, MRC Integrative Epidemiology Unit · active
“funded by the UK Medical Research Council as part of the MRC Integrative Epidemiology Unit”
World Cancer Research Fund · active
“In work funded by the World Cancer Research Fund”
Source: lab pages
12 platforms and techniques
Analyzes
EpiGraphDB, OpenGWAS, MR-Base, ASQ, MendelVar, CScape, FATHMM
Techniques
Knowledge graphs, Language models, Mendelian randomization and genetic colocalization, Target trial emulation, Cross-ancestry proteome-wide MR
Source: lab pages
No openings posted
Poster
Fri Oct 23
2:30 pm
Evaluating discordance between expression quantitative trait loci and protein quantitative trait loci using enrichment analysis
Statistical Genetics and Genetic Epidemiology
Expression quantitative trait lociQuantitative traitEpidemiologyGenetic epidemiology
Immunopsychiatry: Inflammation and Psychiatry Research Groupimmunopsychiatry.com/team
Wet + dry lab~16 people
Studies inflammation in psychiatric disorders using population cohorts, genetic analyses, proteomics and early-phase clinical trials. Targets causal mechanisms and treatments for depression and schizophrenia.
60 papers since 2024
Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study
Translational Psychiatry, 2025
Immuno-metabolic depression: from concept to implementation
The Lancet Regional Health - Europe, 2024
A novel biomarker of interleukin 6 activity and clinical and cognitive outcomes in depression
Psychoneuroendocrinology, 2024
Source: OpenAlex author A5015663073
Funded by Wellcome Trust, MRC +9 more
MRC, Immunopsychiatry Programme · active
“Funded by the MRC, we are examining:”
MRC, Psychosis Immune Mechanism Stratified Medicine · active
“Funded by the MRC and supported by the NIHR Bristol BRC”
NIHR Bristol BRC, Psychosis Immune Mechanism Stratified Medicine · active
“Funded by the MRC and supported by the NIHR Bristol BRC”
+8 more on the lab page
Source: lab pages
8 platforms and techniques
Techniques
Mendelian randomization, genetic colocalization, trajectory based modelling, machine learning, polygenic risk score, causal inference, multi-omics, immunotherapy clinical trials
Source: lab pages
Currently hiring
“Golam is pleased to consider applications from prospective PhD students, staff and interns.”
Source: lab positions page
Poster
Thu Oct 22
4:15 pm
Relationship between IL6 activity, inflammatory markers and psychiatric conditions: findings from UK Biobank cohort and genetic analyses
Complex Traits and Polygenic Disorders
Collaborators: Norwegian Institute of Public Health, NIHR Bristol Biomedical Research Centre +1 more
DepressionGenome-wide association studyImmune systemProteomics
Lifecourse GWAS Consortiumlifecourse-gwas.github.io
Dry lab~15 people
Analyzes genome-wide association results from 50 cohort studies and biobanks, stratified by age, sex and ancestry. Builds polygenic risk scores and Mendelian-randomisation instruments across age.
17 papers since 2024
A structural mean modeling Mendelian randomization approach to investigate the lifecourse effect of adiposity: applied and methodological considerations
American Journal of Epidemiology, 2025
The role of body image dissatisfaction in the relationship between body size and disordered eating and self-harm: complimentary Mendelian randomization and mediation analyses
Molecular Psychiatry, 2024
A Qualitative Analysis of the Perceptions of Stakeholders Involved in Vector Control and Vector-Borne Disease Research and Surveillance in Orinoquia, Colombia
Tropical Medicine and Infectious Disease, 2024
Source: OpenAlex author A5047148652
4 platforms and techniques
Techniques
Genome-wide association studies, Mendelian randomisation, Polygenic risk scores, Cross-cohort harmonisation
Source: lab pages
No funding stated · No openings posted
Poster
Fri Oct 23
2:30 pm
Genetic effects on complex traits exhibit distinct patterning across the lifecourse
Statistical Genetics and Genetic Epidemiology
Collaborators: The University of Queensland, University of Bergen +5 more
Complex traitsGenetic epidemiologyGenome-wide association studyMethodology
Skin Genetics Consortiumskingeneticsconsortium.org
Dry lab~59 people
Analyzes population-scale genomic data from biobanks and electronic health records to study skin diseases and traits. Shares results through the Skin Knowledge Portal.
Funded by Leo Foundation
Leo Foundation · active
“This initial project is funded by the Leo Foundation.”
Source: lab pages
3 platforms and techniques
Techniques
GWAS, Mendelian randomization, EHR phenotype genetic analysis
Source: lab pages
No openings posted
Poster
Wed Oct 21
2:30 pm
★ Reviewers’ Choice
Utilizing the Genotype-Phenotype Map (GPMap) to uncover shared skin biology and prioritize drug targets
Statistical Genetics and Genetic Epidemiology
Complex diseasesComputational toolsGenetic epidemiologyGenome-wide association study
1 more presenter — research group not yet identified

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