Northeastern University at ASHG 2026

Oct 20–24, 2026 Montréal, Canada ~7.5k attendees Website

Northeastern University brings 7 presentations from 4 research groups to ASHG 2026 in Montréal. Its program centres on rare-disease genome sequencing, addiction genetics, and computational genetics. The Genome Technology Laboratory brings methylation-aware long-read sequencing for undiagnosed rare disease, the Laboratory of Addiction Genetics brings a hybrid rat diversity panel for opioid-use disorder, and the Channing Division of Network Medicine brings COPD vascular-disease epigenomics.

Organization	ASHG 2026 Attendance
Northeastern University Boston, Massachusetts	2 PhD Students · 2 Undergrads · 1 Postdoc · 1 PI
Laboratory of Addiction Geneticsbryantlab.sites.northeastern.edu Wet + dry lab~18 people Studies genes, behavior and neuroscience in mouse and rat models using CRISPR-Cas9, quantitative PCR, liquid chromatography mass-spectrometry and CUT&RUN sequencing. Targets opioid and cocaine addiction. 16 papers since 2024 › Cross-Sensitization between Binge Eating and Binge Drinking in a Novel C57BL/6NJ Murine Model of Disease Comorbidity Requires PDE4B Activation Journal of Neuroscience, 2025 Genome-wide association studies with experimental validation identify a protective role for B lymphocytes against chronic post-surgical pain British Journal of Anaesthesia, 2024 The ultrasonic vocalization (USV) syllable profile during neonatal opioid withdrawal and a kappa opioid receptor component to increased USV emissions in female mice Psychopharmacology, 2024 Source: OpenAlex author A5065191295 Funded by NIH, NIDA › NIH · active “awarded an NIH grant for 3.5 million dollars” NIDA, Center of Excellence in Omics, Systems Genetics, and the Addictome pilot grant · 2019; 1-year grant “awarded a pilot grant through the NIDA Center of Excellence in Omics, Systems Genetics, and the Addictome” Source: lab pages 15 platforms and techniques › Runs quantitative PCR, liquid chromatography mass-spectrometry, CUT&RUN sequencing, 3-dimensional recording system, western blot, immunohistochemistry, proteomics, conditioned place preference Techniques CRISPR-Cas9, targeted adeno-associated viral injections, open-field locomotion, machine learning, reduced complexity crosses, Carworth Farms White mouse model, rat reduced complexity cross Source: lab pages No openings posted	Symposium Fri Oct 23 8:35 am Part of Translational Models for Substance Use Disorders The hybrid rat diversity panel as a valuable strategy to model stages of opioid use disorder Room 516BC/Level 5
Channing Division of Network Medicinesites.google.com/channing.harvard.edu/cdnm/home Works in population genetics and computational genetics.	Poster Thu Oct 22 4:15 pm Part of Epigenomics Poster Thursday Session Epigenome-Wide Profiling of Nasal Epithelium Reveals Vascular Inflammation and Hypoxia Signatures in COPD-Associated Pulmonary Vascular Disease Exhibit & Poster Hall · Board 7052T Collaborators: Brigham and Women's Hospital, Medical University of Graz +1 more BioinformaticsEpigeneticsEpigenome-wide association studiesMethylation
Huang Laboratoryaugusthuanglab.org/team Works in computational genetics.	Poster Fri Oct 23 2:30 pm Part of Omics Technologies Poster Friday Session Benchmarking Single-Nucleus Multiomic Profiling for Somatic Mutation Detection and Cell Type Identification in Alzheimer's Disease Brain Exhibit & Poster Hall · Board 8125F Collaborators: Boston Children's Hospital, Broad Institute +1 more Alzheimer’s diseaseBrain/nervous systemExome/genome sequencingMulti-omics
Genome Technology Laboratory Works in rare disease and computational genetics.	Talk Wed Oct 21 1:59 pm Part of Advances in Clinical Genomics in the Era of AI, Long-Read Sequencing, Precision Medicine, and Genomic Care Delivery Scalable, routine, methylation-aware long read genome sequencing of undiagnosed rare disease samples Room 710B/Level 7 Laboratory genetics and genomicsClinical geneticsCopy number/structural variationHaplotype Session Thu Oct 22 8:15 am Innovation Through Adversity: How Global Genomics Partnerships Are Evolving to Meet New Challenges Room 518/Level 5 Poster Fri Oct 23 2:30 pm ★ Reviewers’ Choice Part of Laboratory Genetics and Genomics Poster Friday Session Scalable, Routine, Methylation-aware Long Read Genome Sequencing of Undiagnosed Rare Disease Samples Exhibit & Poster Hall · Board 2054F Clinical geneticsCopy number/structural variationHaplotypeLaboratory genetics and genomics
2 more presenters — research group not yet identified

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