ASHG 2026 · Tier 1 Academic

Duke University at ASHG 2026

Name: ASHG 2026 Annual Meeting
Start: 2026-10-20
End: 2026-10-24
Location: Montréal

Durham, North Carolina

Duke University at ASHG 2026 in Montréal: 12 presentations (11 posters, 1 platform talk); 7 research groups.

presentations on the program

research groups identified

sessions invited to or moderated

Explore everyone at ASHG 2026 →

Organization	ASHG 2026 Attendance
Duke University Durham, North Carolina	7 PhD Students · 4 PIs · 1 Postdoc
Gersbach Labgersbachlab.org Wet + dry lab~38 people Develops CRISPR/Cas9, TALEN and zinc-finger editing in cells and mouse models. Applies these tools to gene therapy, regenerative medicine and disease modeling. 44 papers since 2024 › Epigenome editing technologies for discovery and medicine Nature Biotechnology, 2024 Deciphering the impact of genomic variation on function Nature, 2024 Multicenter integrated analysis of noncoding CRISPRi screens Nature Methods, 2024 Source: OpenAlex author A5076902342 Funded by NSF, Duke Institute for Brain Sciences +4 more › NSF, Graduate Research Fellowship · 2026 “Congratulations to Emilie for receiving the NSF Graduate Research Fellowship” Duke Institute for Brain Sciences, PhD Fellowship · 2026 “Congratulations to Sophie for receiving a Duke Institute for Brain Sciences PhD Fellowship” Duke School of Medicine Precision Genomics Collaboratory-OBGE, graduate student pilot research grant · 2026 “Congratulations to Danai for receiving a Duke School of Medicine Precision Genomics Collaboratory-OBGE graduate student pilot research grant” +3 more on the lab page Source: lab pages 12 platforms and techniques › Runs CRISPR/Cas9, Zinc finger nucleases, TALENs, AAV-CRISPR, CRISPR screens, CRISPR-based epigenome editing Techniques Genetic reprogramming, Optogenetics, Stem cell transplantation, Mouse models of Duchenne muscular dystrophy, Induced pluripotent stem cells, Protein engineering Source: lab pages Currently hiring › “We are actively seeking qualified postdoctoral candidates” Source: lab positions page	Talk Thu Oct 22 11:45 am Large-scale perturbational analysis of schizophrenia-associated genes in human neurons reveals the transcriptional consequences and convergence of disease genes and loci Cross-Disease Insights into Neuropsychiatric and Neurodegenerative Disorders Collaborators: University of Florida, University of North Carolina at Chapel Hill Psychiatric geneticsGenome editing/CRISPRSingle-cellNeurogenetics Poster Thu Oct 22 4:15 pm Investigating Regulatory Elements and Noncoding Variants Conferring Risk for Psychiatric Disorder Complex Traits and Polygenic Disorders Collaborators: University of North Carolina at Chapel Hill Psychiatric geneticsGene regulationGenome editing/CRISPRComplex diseases Poster Fri Oct 23 2:30 pm Understanding non-coding contributions to neuropsychiatric disorder loci via CRISPR-based screens Complex Traits and Polygenic Disorders Complex diseasesGene regulationGenetic variationGenome editing/CRISPR
Gregory Labneurosurgery.duke.edu/gregory-lab Wet + dry lab~13 people Runs 10x Genomics Chromium, Visium and Xenium assays and analyzes whole-genome, exome and bulk RNA-seq data. Studies brain tumors, MS and Alzheimer’s disease with collaborators. 66 papers since 2024 › Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction Nature Communications, 2025 Spatial transcriptomics reveals segregation of tumor cell states in glioblastoma and marked immunosuppression within the perinecrotic niche Acta Neuropathologica Communications, 2024 PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma Journal of Clinical Investigation, 2024 Source: OpenAlex author A5004078699 14 platforms and techniques › Works with 10x Genomics Chromium scRNAseq/snRNAseq, 10x Genomics Visium spatial gene expression, 10x Genomics Xenium in situ sequencing, Whole-genome sequencing, Exome sequencing, Bulk RNA-Seq, Spatial transcriptomics, Long-read sequencing Techniques Single-cell and spatial expression profiling, Multi-omic biomarker discovery, Cell-neighborhood interaction analysis, Spatial RNA splicing analysis, Hydroxyl-cholesterol remyelination treatment, Demyelinating pre-clinical MS model Source: lab pages No funding stated · No openings posted	Moderator Thu Oct 22 11:00 am Pivoting from Gene-Level Analyses to Isoform-Resolved Biology Moderator Thu Oct 22 2:30 pm Awards Recognition & Plenary Abstract Session II Poster Fri Oct 23 2:30 pm In Situ Sequencing Reveals Distinct Host-Herpesvirus Microenvironments in MS Spinal Cord Lesions Complex Traits and Polygenic Disorders Collaborators: Cleveland Clinic Spatial transcriptomicsNeurodegenerationGenomics
Allen Labpeople.duke.edu/… Dry lab~4 people Develops statistical methods for exome sequencing, whole-genome sequencing and case-parent sequencing data. Applies them to susceptibility loci, rare variants and complex disease-gene mapping. 21 papers since 2024 › Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER Cell Genomics, 2025 Bayesian estimation of allele-specific expression in the presence of phasing uncertainty Bioinformatics, 2025 Deciphering the impact of genomic variation on function Nature, 2024 Source: OpenAlex author A5026198048 7 platforms and techniques › Analyzes whole-exome sequencing, whole-genome sequencing, case-parent sequencing Techniques rare-variant association testing, haplotype-sharing models, multi-variant regression, population-stratification correction Source: lab pages No funding stated · No openings posted	Moderator Thu Oct 22 8:15 am Sequence Models Transforming Genetics and Genomics Poster Fri Oct 23 2:30 pm TrioBEASTIE: A Bayesian model for classifying inheritance of allelic imbalance, applied to children with complex medical disorders Statistical Genetics and Genetic Epidemiology Collaborators: University of Massachusetts Chan Medical School Clinical geneticsComputational toolsInheritance patternsStatistical genetics
Biostatistics Groupanesthesiology.duke.edu/research/biostatistics Dry lab~5 people Analyzes clinical, genomic, basic-science, microarray and proteomic data with statistical modeling and machine learning. Supports research within Duke Anesthesiology. 44 papers since 2024 › An osteoarthritis pathophysiological continuum revealed by molecular biomarkers Science Advances, 2024 A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation Communications Biology, 2024 Genetic variants associated with immune-mediated liver injury from checkpoint inhibitors Hepatology Communications, 2024 Source: OpenAlex author A5043275152 8 platforms and techniques › Analyzes Microarray Techniques Factor analysis, Missing-data methods, Survival analysis, Genetic association methods, Feature identification and classification, Machine learning, Bioinformatics Source: lab pages No funding stated · No openings posted	Poster Fri Oct 23 2:30 pm Enhanced Genetic Prediction of Age-of-Onset of Alzheimer’s Diseases Beyond Linearity via Integrating Mutual Information and Hierarchical Neural Networks Artificial Intelligence and Machine Learning Collaborators: University of Miami Alzheimer’s diseaseDeep learningPolygenic risk scoreGenome-wide association study
Kantor Labneuro.duke.edu/research/faculty-labs/kantor-lab Wet lab~2 people Develops AAV, lentiviral and CRISPR-based gene-editing tools through custom cloning and vector production. Supports basic and translational rare-disease research. 9 papers since 2024 › Cell-specific DNA methylation in human alpha and beta cells regulates gene expression in type 2 diabetes Nature Metabolism, 2026 Trends and challenges of AAV-delivered gene editing therapeutics for CNS disorders: Implications for neurodegenerative disease Molecular Therapy — Nucleic Acids, 2025 The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders Nature Communications, 2024 Source: OpenAlex author A5062881503 Funded by National Institutes of Health, Michael J. Fox Foundation for Parkinson's Research +1 more › National Institutes of Health · 2022 - 2027 “Awarded by National Institutes of Health · 2022 - 2027” Michael J. Fox Foundation for Parkinson's Research · 2022 - 2025 “Awarded by Michael J. Fox Foundation for Parkinson's Research · 2022 - 2025” Kallyope, Inc · 2023 - 2025 “Awarded by Kallyope, Inc · 2023 - 2025” Source: lab pages 13 platforms and techniques › Runs Adeno-Associated Vectors (AAVs), Integrase-Competent Lentiviral Vectors (ICLVs), Integrase-Deficient Lentiviral Vectors (IDLVs), g-Retroviral Vectors, Rabies Viruses (RVs), HIV-1-based vectors, CRISPR/Cas9 RGNs Techniques Custom plasmid cloning, Viral vector production, CRISPR-based gene editing, RNAi and mi-shRNAs, Optogenetics, In-vitro and in-vivo gene delivery Source: lab pages No openings posted	Poster Wed Oct 21 2:30 pm A novel all-in-one adeno-associated vector-based system for efficient CRISPR/Cas9 editing: in vitro and in vivo validations in liver and CNS Genetic Therapies and Precision Medicine Collaborators: Washington University in St. Louis, University of Pennsylvania Gene therapyGene regulationGenome editing/CRISPR
Neurology, Translational Brain Sciencesscholars.duke.edu/organization/51112617/overview Wet + dry lab~11 people Analyzes single-cell multi-omics, ATAC-seq, ECoG, EEG and MEG data in neurological disease and cognition. Develops Alzheimer’s mouse models and therapies. 1 paper since 2024 › A diagnostic plasma omics-biomarker for Alzheimer’s disease informed by microglial single-cell transcriptomics: A pilot study bioRxiv (Cold Spring Harbor Laboratory), 2026 Source: OpenAlex author A5135363353 Funded by National Institute on Aging, National Institutes of Health +3 more › National Institute of Diabetes and Digestive and Kidney Diseases, The Gut Brain Parkinson's Disease Consortium (GBPDC): Coordinating and Data Management Center (CDMC) · 2024 - 2029 “Research Co-Principal Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029” National Institute on Aging, Untangling the diversity in the genetic architecture of late-onset Alzheimer's disease using single cell multi-omics · 2026 - 2028 “"Untangling the diversity in the genetic architecture of late-onset Alzheimer's disease using single cell multi-omics"; "Awarded by National Institute on Aging"; "2026 - 2028"” National Institutes of Health, Untangling the diversity in the genetic architecture of late-onset Alzheimer's disease using single cell multi-omics · 2022 - 2027 “Research Principal Investigator · Awarded by National Institutes of Health · 2022 - 2027” +2 more on the lab page Source: lab pages 13 platforms and techniques › Works with single-nucleus multi-omics, ATAC-seq, ECoG, µECoG, EEG, MEG, fMRI Techniques neural power analysis, connectivity measures, decoding algorithms, polygenic risk score, CRISPR/Cas-lentiviral vector, Alzheimer's disease mouse models Source: lab pages No openings posted	Poster Fri Oct 23 2:30 pm Integrative single-cell multi-omics of African ancestry Alzheimer’s disease brains reveals APOE ε4- and sex- dependent effects on glial ribosomal gene expression and translation pathways Complex Traits and Polygenic Disorders Alzheimer’s diseaseGene regulationMulti-omicsNeurodegeneration
Wray Labsites.duke.edu/wraylab Wet + dry lab~9 people Studies transcriptional regulation with iPSCs, single-cell RNA-seq, ATAC-seq and comparative genomics. Research spans primates, sea urchins and Heliconius butterflies to explain regulatory evolution. 23 papers since 2024 › A human-specific enhancer fine-tunes radial glia potency and corticogenesis Nature, 2025 Lepidopteran scale cells derive from sensory organ precursors through a canonical lineage Development, 2025 Source: OpenAlex author A5081032810 Funded by NSF, TriCEM +1 more › NSF, Rules of Life · active “project funded by an NSF Rules of Life grant” TriCEM “Tania is awarded the TriCEM grant” PGC, student pilot grant “Tania is awarded the PGC student pilot grant” Source: lab pages 9 platforms and techniques › Works with single-cell RNA-seq, ATAC-seq, Seurat Techniques iPSCs, cell culture models, comparative genomics, primate tissue samples, sea urchins, Heliconius butterflies Source: lab pages No openings posted	Poster Wed Oct 21 2:30 pm Genetic background modifies cis-regulatory activity in human iPSCs Evolutionary and Population Genetics Collaborators: Altius Institute for Biomedical Sciences GenomicsComplex traitsNatural selectionGene regulation
3 more presenters — research group not yet identified

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