Biotech companies at ACT 2026

Nov 15–18, 2026 San Antonio, TX ~1.4k attendees Website

22 biotech companies are at ACT 2026 — 28 presentations on the program. Most represented: Spyre Therapeutics (2 on the program), Enveda (1 on the program), Neurocrine Biosciences (1 on the program). 7 of them have their own page in this guide. As of Oct 8, 2026.

All 231 organizations at ACT 2026 →

Topic
Top represented
Showing 1–17 of 22 organizations
OrganizationACT 2026 Attendance
Biotech companies
Clinical-stage biotech developing half-life-extended antibodies and antibody combinations for inflammatory bowel disease and other immune-mediated diseases.
Poster
Mon Nov 16
5:00pm–6:30pm
Combination Toxicity Assessments of SPY001, SPY002, and SPY003, Half-Life Extended Monoclonal Antibodies Targeting α4β7, TL1A, and IL-23 (P121)
Nelson Exhibit Ballroom · Poster P121
Biologics and new modalities
Enveda
Boulder, CO
Biotech companies
Biotech discovering medicines from natural-product chemistry with AI; chairs a course on genetic toxicology in drug development.
Talk
Sun Nov 15
1:00pm–1:30pm
Part of Navigating Genetic Toxicology through Drug Development: Interface of Practice, Strategy, and Regulatory Principles (CE7)
Genetic Toxicology in Drug Development: An Overview of Mechanisms, Methods, and Regulatory Expectations (CE7-1)
Genetic toxicology
Talk
Sun Nov 15
4:00pm–4:30pm
Part of Navigating Genetic Toxicology through Drug Development: Interface of Practice, Strategy, and Regulatory Principles (CE7)
Panel Discussion with Case Studies (CE7-Panel)
Genetic toxicology · with Litron Laboratories
◆Gold Supporter
Biotech companiesGold Supporter
Biopharmaceutical company developing treatments for neurological, psychiatric, endocrine and immune disorders.
Session
Tue Nov 17
2:00pm–5:00pm
From Policy to Practice: Progress on the FDA’s 2025 Roadmap to Reduce Animal Use in Antibody Platform Development (S12)
New approach methods · Regulatory · with Lilly
  1. 2:00pmWelcome and Overview (S12-1)Neurocrine Biosciences
  2. 2:05pmA Brief History of Regulatory Efforts to Reduce Animal Use in Drug Development (S12-2)Lilly
  3. 2:20pmThe FDA Roadmap and Adoption of NAMs for Regulatory Decision Making (S12-3)U.S. Food and Drug Administration
  4. 2:50pmIndustry Experience: DruSafe/BioSafe Survey (S12-4)Agios Pharmaceuticals
  5. 3:45pmNAM Qualification Pathway for an ISTAND Drug Development Tool (S12-5)Integral Molecular
Talk
Tue Nov 17
2:00pm–2:05pm
Part of From Policy to Practice: Progress on the FDA’s 2025 Roadmap to Reduce Animal Use in Antibody Platform Development (S12)
Welcome and Overview (S12-1)
New approach methods
Biotech companies
Biotech developing medicines for neurodegenerative diseases that are engineered to cross the blood–brain barrier.
Session
Mon Nov 16
9:00am–12:00pm
Beyond the Vessel Wall: Translational Insights into Vascular Inflammation (S03)
Pathology · Translational safety · with Labcorp
  1. 9:00amIntroduction to Vascular Inflammation (S03-1)Korsana Biosciences
  2. 9:15amDrug Induced Vascular Injury (DIVI) Related to Biologic Therapies: Mechanisms and Sensitivity (S03-2)International Academy of Toxicologic Pathology
  3. 9:45amA Regulatory Perspective (S03-3)ToxStrategies
  4. 10:45amBiomarkers of Vascular Injury (S03-4)Merck
  5. 11:15amInnovative Tools and Future Directions (S03-5)Kymera Therapeutics
Talk
Mon Nov 16
9:00am–9:15am
Part of Beyond the Vessel Wall: Translational Insights into Vascular Inflammation (S03)
Introduction to Vascular Inflammation (S03-1)
Pathology
QurAlis
Cambridge, MA
Biotech companies
Biotech developing precision medicines for ALS, frontotemporal dementia and other neurodegenerative diseases.
Talk
Tue Nov 17
9:00am–9:05am
Part of Overcoming the Blood-Brain Barrier and Translational Challenges in the Nonclinical Development of CNS Drugs (S08)
Introduction (S08-1)
Neurotoxicology
Session
Tue Nov 17
9:00am–12:00pm
Overcoming the Blood-Brain Barrier and Translational Challenges in the Nonclinical Development of CNS Drugs (S08)
Neurotoxicology · with Florian Consulting
  1. 9:00amIntroduction (S08-1)QurAlis
  2. 9:05amBeyond the Barrier: Unlocking Drug Penetration into the CNS (S08-2)Bedard ADME-Tox Solutions
  3. 9:30amMedicinal Chemistry Strategies to Improve Brain Penetrance with Small Molecules (S08-3)Olorin Consulting
  4. 9:50amNonclinical Developmental Considerations for Neuronal Delivery of Oligonucleotides (S08-4)Lilly
  5. 10:45amThe FORCETM Platform Delivers Safe Concentrations of Oligonucleotides to the Central Nervous System of Non-Human Primates (S08-5)Dyne Therapeutics
  6. 11:15amToxicology Challenges and Opportunities for Gene Therapy: CNS-Related Assessment in Animal Models (S08-6)Altasciences
Regeneron
Tarrytown, NY
Biotech companies
Biotech company that discovers, develops and markets antibody medicines and is building gene therapies, including for genetic hearing loss.
Session
Wed Nov 18
9:00am–12:00pm
Do You Hear What I Hear? Evaluating Otic and Vestibular Toxicity in Clinical Development (S14)
Neurotoxicology · Translational safety · with CBSET
  1. 9:00amIntroduction to Ototoxicity: Cochlear and Vestibular Toxicity (S14-1)Turner Scientific
  2. 9:25amThe Blood-Labyrinth-Barrier (BLB) and Biodistribution of a mAb into the Ear to Assess Ototoxicity (S14-2)Amgen
  3. 9:50amCase Study of DB-OTO: An AAV Gene Therapy for Auditory Neuropathy due to Otoferlin Variants (S14-3)Regeneron
  4. 10:45amPathology of Candidates Targeting Otic Conditions (S14-4)Greenfield Pathology Services
  5. 11:05amIntegrated Preclinical Approaches for Assessing Ototoxicity (S14-5)Cilcare
  6. 11:25amRegulatory Perspective: Guidance, Expectations, and Safety Pharmacology Assessment (S14-6)U.S. Food and Drug Administration
Talk
Wed Nov 18
9:50am–10:15am
Part of Do You Hear What I Hear? Evaluating Otic and Vestibular Toxicity in Clinical Development (S14)
Case Study of DB-OTO: An AAV Gene Therapy for Auditory Neuropathy due to Otoferlin Variants (S14-3)
Biologics and new modalities · Neurotoxicology
Biotech companies
Biotech company developing medicines for rare diseases, including inherited blood disorders such as pyruvate kinase deficiency and thalassemia.
Talk
Tue Nov 17
2:50pm–3:15pm
Part of From Policy to Practice: Progress on the FDA’s 2025 Roadmap to Reduce Animal Use in Antibody Platform Development (S12)
Industry Experience: DruSafe/BioSafe Survey (S12-4)
New approach methods
Aligos Therapeutics
South San Francisco, CA
Biotech companies
Biotech developing medicines for chronic hepatitis B and liver disease; presents preclinical data on an HBV antisense oligonucleotide.
BioMarin
San Rafael, CA
Biotech companies
Biotech company developing and marketing treatments for rare genetic diseases, including enzyme replacement therapies.
Session
Wed Nov 18
2:00pm–3:15pm
The Versatile Toxicologist: How to Leverage Expertise into Opportunity (S16)
Careers · with Bristol Myers Squibb
  1. 2:00pmConventional and Unconventional Trajectories to a Toxicologist Career in the Pharmaceutical Sector (S16-1)Boehringer Ingelheim
  2. 2:20pmTransitioning from Government Regulator to the Private Sector (S16-2)BlueRock Therapeutics
  3. 2:40pmSo You Want to Be a Consultant? (S16-3)Biologics Consulting
Biotech companies
Clinical-stage cell therapy developer owned by Bayer, building cell replacement treatments for neurological and eye diseases.
Talk
Wed Nov 18
2:20pm–2:40pm
Part of The Versatile Toxicologist: How to Leverage Expertise into Opportunity (S16)
Transitioning from Government Regulator to the Private Sector (S16-2)
Careers
Disc Medicine
Watertown, MA
Biotech companies
Biotech developing hematology medicines that act on hepcidin and iron; presents carcinogenicity risk assessments for two antibodies.
Poster
Mon Nov 16
5:00pm–6:30pm
Biotech companies
Biotech developing oligonucleotide medicines for neuromuscular diseases; presents data on delivering them to the central nervous system of monkeys.
Talk
Tue Nov 17
10:45am–11:15am
Part of Overcoming the Blood-Brain Barrier and Translational Challenges in the Nonclinical Development of CNS Drugs (S08)
The FORCETM Platform Delivers Safe Concentrations of Oligonucleotides to the Central Nervous System of Non-Human Primates (S08-5)
Biologics and new modalities · Neurotoxicology
Editas Medicine
Cambridge, MA
Biotech companies
Genome-editing company developing in vivo CRISPR-based gene therapies.
Talk
Mon Nov 16
3:45pm–4:15pm
Part of In Vivo Gene Therapies: Breakthrough Innovations, Regulatory Roadmaps, and Development Challenges (S04)
ADME and Toxicology Considerations for the Advancement of Non-viral Gene Therapy Products (S04-4)
Biologics and new modalities · Bioanalysis and biomarkers
EM
EvoN Medics
Biotech companies
Developer of products for neurological conditions; presents a rat study of a drug protecting against aluminum-induced neurotoxicity.
Poster
Mon Nov 16
5:00pm–6:30pm
IDEAYA Biosciences
South San Francisco, CA
Biotech companies
Oncology biotech developing precision medicines, including synthetic-lethality drugs, for genetically defined cancers.
Session
Mon Nov 16
9:00am–12:00pm
From China to the World: De-risking Nonclinical Safety Packages to Ensure Regulatory Acceptance (S01)
Regulatory · with Windward Bio
  1. 9:00amWorking with Chinese CROs: Benefits, Risks and Best Practices (S01-1)BiotechGo
  2. 9:40amChina GLP Toxicology Studies: Local Nuances for Global Alignment (S01-2)WuXi AppTec
  3. 10:45amPathology Without Borders: Best Practices for Pathology Review and Digital Data Exchange in China (S01-3)Greenfield Pathology Services
  4. 11:20amNavigating OECD MAD: Regulatory Expectations for GLP Compliance Across Regions (S01-4)
Ignota Labs
Cambridge, UK
Biotech companies
AI-driven company that rescues shelved drug candidates, using a machine-learning safety platform to predict off-target toxicity mechanisms.
Talk
Sun Nov 15
10:00am–10:30am
Part of From Predictive Models to Collaborative Intelligence: The Role of Agentic AI in the Future of Toxicology (CE2)
Leveraging Agentic AI to Reassess and Optimize Previously Failed Compounds (CE2-5)
In silico and AI
Biotech companies
Develops RNA-targeted antisense oligonucleotide medicines, with marketed drugs for neurological and cardiometabolic diseases.
Poster
Mon Nov 16
5:00pm–6:30pm
ION269: Nonclinical Safety and Pharmacokinetic Characterization of an MSPA-Modified ASO for Alzheimer’s Disease in Down Syndrome (P209)
Nelson Exhibit Ballroom · Poster P209
Biologics and new modalities · Neurotoxicology

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