University of Nebraska Medical Center at AAPS 2026 PharmSci 360

Oct 25–28, 2026 New Orleans, LA ~4k attendees Website

University of Nebraska Medical Center brings 12 presentations to AAPS 2026 PharmSci 360 in New Orleans. Its work centres on nanoparticle and prodrug delivery, with lipid nanoparticles carrying mRNA or microRNA drugs into pancreatic cancer, liver disease and medulloblastoma. Projects also include steroid prodrugs aimed at the kidney and joints, and how different HIV regimens control the virus in the brain.

OrganizationAAPS 2026 PharmSci 360 Attendance
Talk
Mon Oct 26
3:15pm–3:30pm
Part of Rapid Fire: Novel Modalities, Targeted Delivery and Disease Focused Translational Applications
Systemic Control, CNS Escape: Regimen-Specific Differences in Brain HIV Suppression
207
Preclinical, Clinical, and Translational Sciences
Poster
Mon Oct 26
3:30pm–4:30pm
Dual Targeting of Hedgehog Signaling and miR-96 Using Lipid Nanoparticles Attenuates Experimental Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Solution Center · Poster M1530-03-15
Formulation and Delivery - Biomolecular
Poster
Tue Oct 27
9:30am–10:30am
Evaluation of Integrated Pharmacokinetics and Dose Simulation of p-CH3-2a, a Novel Aldo-Keto Reductase 1C3 Inhibitor for Castration-Resistant Prostate Cancer
Solution Center · Poster T0930-06-33
Preclinical, Clinical, and Translational Sciences
Poster
Tue Oct 27
10:30am–11:30am
Development of the Thermoresponsive Dexamethasone Prodrugs as a Local Therapy for Osteoarthritis
Solution Center · Poster T1030-03-17
Formulation and Delivery - Chemical
Poster
Tue Oct 27
11:30am–12:30pm
CXCR4-Targeted Lipid Nanoparticle Platform for mRNA Delivery in Pancreatic Ductal Adenocarcinoma
Solution Center · Poster T1130-02-09
Formulation and Delivery - Biomolecular
Poster
Tue Oct 27
11:30am–12:30pm
Lipid Nanoparticle-Mediated Delivery of SRX3305 and miR-217 Hairpin Inhibitor for Combination Therapy of Medulloblastoma
Solution Center · Poster T1130-03-16
Formulation and Delivery - Biomolecular
Poster
Tue Oct 27
12:30pm–1:30pm
Optimization of PEGylated Dexamethasone Polymeric Prodrugs for Targeted Treatment of Focal Segmental Glomerulosclerosis: Impact of PEG Molecular Weight on Renal Delivery, Efficacy, and Safety
Solution Center · Poster T1230-03-17
Formulation and Delivery - Chemical
Poster
Tue Oct 27
2:30pm–3:30pm
Pharmacokinetics and Bone Marrow Accumulation of R-IMAE in a Murine Model of Acute Radiation Syndrome (ARS)
Solution Center · Poster T1430-06-35
Preclinical, Clinical, and Translational Sciences
Poster
Tue Oct 27
3:30pm–4:30pm
Development of Fluorinated-Based CXCR4 Targeted Nanoparticles to Enhance the Delivery of a Geranylgeranyl Diphosphate Synthase Inhibitor for Metastatic Osteosarcoma
Solution Center · Poster T1530-01-04
Formulation and Delivery - Chemical
Talk
Tue Oct 27
3:45pm–4:00pm
Part of Rapid Fire: Breakthrough Technologies for Drug Product Development and Evaluation
Optimization of PEGylated-Dexamethasone-Polymeric Prodrugs for Targeted Focal Segmental Glomerulosclerosis
217-219
Formulation and Delivery
Poster
Wed Oct 28
10:30am–11:30am
An Injectable In Situ Hydrogel-Forming Polymer Prodrug Depot for Local Modulation of Periodontal Inflammation and Alveolar Bone Loss
Solution Center · Poster W1030-01-05
Formulation and Delivery - Chemical
Poster
Wed Oct 28
11:30am–12:30pm
Systemic Control, CNS Escape: Regimen-Specific Differences in Brain HIV Suppression Revealed in a Humanized Microglial Mouse Model
Solution Center · Poster W1130-06-31
Preclinical, Clinical, and Translational Sciences

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