ASHG 2026 · Tier 2–3 Academic

Nagoya City University at ASHG 2026

Nagoya, Japan

Nagoya City University at ASHG 2026 in Montréal: 6 presentations (6 posters); 3 research groups.

6
presentations on the program
3
research groups identified

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OrganizationASHG 2026 Attendance
Nagoya City University
Nagoya, Japan
4 PhD Students · 2 Clinicians
神経グループncu-ped.com/treatment_g/nerve.php
Wet lab
Studies pediatric neurological disorders using genetic analysis, MRI, EEG, iPS cells, brain organoids and model mice. Uses them for diagnosis and disease-mechanism research in children.
11 papers since 2024
Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity
Nature Immunology, 2025
Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming
Nature, 2024
Clinical characteristics of SARS-CoV-2-associated encephalopathy in children: Nationwide epidemiological study
Journal of the Neurological Sciences, 2024
Source: OpenAlex author A5004557264
9 platforms and techniques
Runs
EEG, Genetic testing, Muscle biopsy, Genetic diagnosis
Techniques
Genetic analysis, Model mice, Brain organoids, iPS cells, Gene editing
Source: lab pages
No funding stated · No openings posted
Poster
Wed Oct 21
2:30 pm
MYCN gain-of-function variant alters cortical neuron production in human brain organoids
Mendelian Phenotypes
Collaborators: Nagoya University, University of Kansas Medical Center
NeurodevelopmentalMolecular pathophysiologyMendelian disorderBrain/nervous system
Poster
Thu Oct 22
4:15 pm
A novel de novo DAGLA variant associated with characteristic abnormal eye movements and truncal ataxia
Mendelian Phenotypes
Clinical geneticsExome/genome sequencingMendelian disorderNervous system
Poster
Fri Oct 23
2:30 pm
DNA methylation episignature for OTUD5-related disorder as a complementary tool for variant interpretation
Epigenomics
Collaborators: Nagoya University Hospital, National Center For Child Health and Development +4 more
EpigeneticsIntellectual and developmental disabilityMendelian disorderX-linked disease
内分泌グループncu-ped.com/treatment_g/endocrine.php
Wet + dry lab~4 people
Studies pediatric endocrine disease using next-generation sequencing, CRISPR-Cas9 knockout mice and thyroid organoids. Uses EcoChil data to analyze childhood growth and iodine transport.
4 papers since 2024
Use, efficacy, and safety of desmopressin for congenital nephrogenic diabetes insipidus in children: a nationwide survey
Endocrine Journal, 2026
Histopathological Features of the Testes of a Patient With Congenital Lipoid Adrenal Hyperplasia
IJU Case Reports, 2025
Genotype–Phenotype Correlations in 30 Japanese Patients With Congenital Hypothyroidism Attributable to TG Defects
The Journal of Clinical Endocrinology & Metabolism, 2024
Source: OpenAlex author A5071162531
4 platforms and techniques
Analyzes
Next-generation sequencing
Techniques
CRISPR-Cas9 knockout mice, Thyroid organoids, Comprehensive genetic analysis
Source: lab pages
No funding stated · No openings posted
Poster
Fri Oct 23
2:30 pm
Slc26a7 knockout mice demonstrate a distinct thyroidal response to iodine excess compared with Slc5a5 knockout mice.
Molecular Effects of Genetic Variation
Collaborators: Gunma University, Koshien University
Characterization of disorders
Poster
Fri Oct 23
2:30 pm
Two Cases of Heterozygous IGF1R Variants with Clinical Variability
Complex Traits and Polygenic Disorders
Endocrine systemGenotype-phenotype correlations
名古屋市立大学大医学研究科 新生児・小児医学分野ncu-ped.com
Wet + dry lab~59 people
Analyzes exome, genome, long-read, epigenome, transcriptome, multi-omics and chromosome-microarray data. Uses gene-edited mice and iPS-cell tissue organoids to identify causes in undiagnosed disease.
12 platforms and techniques
Analyzes
Exome analysis, Genome analysis, Long-read sequencing, Chromosome microarray, Epigenome analysis, Transcriptome analysis, Multi-omics analysis
Techniques
Gene-edited mice, iPS-cell tissue organoids, Variant functional analysis, Rare-disease epidemiological surveys, Disease registries and natural-history analysis
Source: lab pages
No funding stated · No openings posted
Poster
Wed Oct 21
2:30 pm
A mild case of Cornelia de Lange Syndrome with a deep intronic NIPBL variant diagnosed through whole-genome sequencing, DNA methylation analysis, and RNA analysis
Molecular Effects of Genetic Variation
Collaborators: Nagoya University, Nagoya University Hospital +2 more
Splicing mechanismsVariant interpretationMethylationGenotype-phenotype correlations

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