ASHG 2026 · Hospital & health system

Montreal Heart Institute at ASHG 2026

Montreal, Quebec

Montreal Heart Institute at ASHG 2026 in Montréal: 5 presentations (5 posters); 3 research groups.

5
presentations on the program
3
research groups identified

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OrganizationASHG 2026 Attendance
Montreal Heart Institute
Montreal, Quebec
2 Postdocs · 2 PhD Students · 1 Staff Scientist
Lettre Labmhi-humangenetics.org/members
Wet + dry lab~13 people
Studies whole-genome sequencing, eQTL, RNA-sequencing, ATAC-sequencing and Hi-C data, and runs CRISPR/Cas9 screens. Focuses on cardiovascular and blood-disease genetics.
40 papers since 2024
Polygenic prediction of body mass index and obesity through the life course and across ancestries
Nature Medicine, 2025
Quercetin Reduces Vascular Senescence and Inflammation in Symptomatic Male but Not Female Coronary Artery Disease Patients
Aging Cell, 2025
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification
Nature Genetics, 2024
Source: OpenAlex author A5080225460
Funded by Canada Research Chair Program
Canada Research Chair Program, Canada Research Chair in Complex Trait Genetics · active
A federal award that pays part of the chair holder's salary plus research support, five years for Tier 2 and seven for Tier 1.
“He holds the Canada Research Chair in Complex Trait Genetics.”
Source: lab pages
10 platforms and techniques
Works with
Whole-genome sequencing, eQTL, RNA-sequencing, ATAC-sequencing, Hi-C
Techniques
CRISPR/Cas9 genome-editing screens, CRISPR knockout, Base editing, Pangenomic approaches, Causal inference methods
Source: lab pages
Currently hiring
“Opportunities exist for talented and motivated individuals ... to join our research activities.”
Source: lab positions page
Poster
Wed Oct 21
2:30 pm
Menopause-associated biological age acceleration and its contribution to increased blood pressure
Complex Traits and Polygenic Disorders
Collaborators: Université de Montréal
Complex traitsCardiovascular systemGenome-wide association studyWomen's health
Poster
Fri Oct 23
2:30 pm
Integrated genotyping, annotation and epigenetic characterization of transposable elements with GraffiTE v1.1
Omics Technologies
Collaborators: University of Arizona, McGill University
BioinformaticsEpigeneticsChromatinMethylation
Poster
Fri Oct 23
2:30 pm
Effect of cardiometabolic traits on hypertrophic cardiomyopathy: a Mendelian randomization study
Complex Traits and Polygenic Disorders
Collaborators: Université de Montréal
Cardiovascular systemMendelian randomizationComplex diseasesEtiology
MedGenimedgeni.org/who-we-are
Wet + dry lab~11 people
Studies IBD with genome-wide association, DNA sequencing, transcriptomics, hiPSC models, FACS, proteomics and metabolomics. Develops genetic, genomic and immunologic biomarkers for diagnosis and therapy response.
26 papers since 2024
Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes
Nature, 2024
Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease
Gastroenterology, 2024
Challenges in IBD Research 2024: Precision Medicine
Inflammatory Bowel Diseases, 2024
Source: OpenAlex author A5060728613
Funded by Canadian Institutes of Health Research, Crohn’s and Colitis Canada +3 more
Canadian Institutes of Health Research · active
“Canadian Institutes of Health Research”
Crohn’s and Colitis Canada · active
“Crohn’s and Colitis Canada”
Genome Québec · active
“Genome Québec”
+2 more on the lab page
Source: lab pages
12 platforms and techniques
Runs
hiPSC Platform, FACS Platform
Techniques
Genome-wide association, Fine mapping, DNA sequencing, Transcriptomic studies, hiPSC models, Monocyte/macrophage cultures, 2D and 3D intestinal epithelial cultures, CRISPR, Serum proteomics, Serum metabolomics
Source: lab pages
No openings posted
Poster
Fri Oct 23
2:30 pm
Genomic, biologic and clinical factors that influence immune response in patients with Inflammatory Bowel Diseases undergoing advanced therapies
Omics Technologies
Collaborators: Université de Montréal, Montreal General Hospital
ProteomicsImmune systemPharmacologic therapy
Taliun Labsgagliano.github.io
Dry lab~9 people
Analyzes CLSA PheWeb, PheWeb2 and UK Biobank data with statistical genetics and machine learning. Studies sex-specific genetics of aging-related neurodegenerative, cardiovascular and kidney diseases.
41 papers since 2024
Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy
Nature Genetics, 2025
Astrocytic RNA editing regulates the host immune response to alpha-synuclein
Science Advances, 2025
A multi-ancestry genetic reference for the Quebec population
medRxiv, 2025
Source: OpenAlex author A5064487935
Funded by NSERC, Brain Canada and Krembil Foundation +10 more
NSERC, Discovery Grant · 2025–2030
Canada's base operating grant for natural-science and engineering labs, typically five years.
“NSERC Discovery Grant: “Methods development to promote the inclusion of X chromosome variation into genetic association analyses””
CIHR, Project Grant: PheWeb-2.0 · 2025–2029
Canada's federal health-research funder, the equivalent of the NIH.
“CIHR Project Grant: “PheWeb-2.0: an interactive tool for generating and testing hypotheses on sex-biased genetic variant-trait associations””
Brain Canada and Krembil Foundation, Accelerator Grant: Neurodegeneration x Immunology · 2026–2028
“Brain Canada & Krembil Foundation Accelerator Grant: Neurodegeneration x Immunology”
+9 more on the lab page
Source: lab pages
9 platforms and techniques
Analyzes
CLSA PheWeb, PheWeb2, UK Biobank
Techniques
Machine learning, Sex-specific Mendelian randomization, Phenome-wide scans, Genome-wide association studies, Multi-omics, Sex-stratified genetic analysis
Source: lab pages
Currently hiring
“We are seeking highly-motivated trainees to join our computational lab located at the Montréal Heart Institute”
Source: lab positions page
Poster
Fri Oct 23
2:30 pm
Shared genetic architecture between kidney-related traits and Parkinson's disease
Complex Traits and Polygenic Disorders
NeurodegenerationGenome-wide association studyComplex traitsGenitourinary system

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