Memorial Sloan Kettering Cancer Center at ASHG 2026

Oct 20–24, 2026 Montréal, Canada ~7.5k attendees Website

Memorial Sloan Kettering Cancer Center brings 7 presentations from 6 research groups to ASHG 2026 in Montréal. Its program centres on cancer genetics, population-scale sequencing, computational analysis, and clinical translation. Carrot-Zhang Lab brings multi-ancestry sequencing of germline effects on cancer progression, Benjamin Greenbaum Lab brings a body mass index score linked to ovarian cancer survival, and Department of Pathology and Laboratory Medicine brings clonal hematopoiesis findings that can mimic inherited variants.

Organization	ASHG 2026 Attendance
Memorial Sloan Kettering Cancer Center New York, New York	2 PhD Students · 2 PIs · 1 Postdoc · 1 Clinician
Carrot-Zhang Labcomponcmsk.org/jian-carrot-zhang-lab Dry lab~12 people Develops statistical and machine-learning methods on whole-genome sequencing and linked electronic health-record data. Studies germline effects on tumor evolution, progression and treatment response. 4 papers since 2024 › Abstract 5222: Multifactorial risks for multiple primary cancers Cancer Research, 2026 Abstract 3093: SLC25A28 is a synthetic lethal target in nucleotide excision repair-deficient cancer Cancer Research, 2026 Abstract 5430: Allostatic load connects tumor genomics, disease trajectory, and pre-diagnosis wearable activity. Cancer Research, 2026 Source: OpenAlex author A5132701398 Funded by National Cancer Institute, CIHR › National Cancer Institute, K99/R00 Pathway to Independence Award “Dr. Carrot-Zhang has received multiple honors, including a K99/R00 Pathway to Independence Award from the NCI” CIHR, Banting Postdoctoral Fellowship Canada's federal health-research funder, the equivalent of the NIH. “a Banting Postdoctoral Fellowship from CIHR.” Source: lab pages 6 platforms and techniques › Analyzes whole-genome sequencing, linked electronic health records Techniques statistical approaches, machine learning, large language models, dynamic modeling Source: lab pages Currently hiring › “We are actively recruiting computational postdocs and graduate students interested in genetic ancestry, germline-somatic interaction and clinical genomics.” Source: lab positions page	Talk Thu Oct 22 11:15 am Part of Cancer Susceptibility: Germline Effects on Risk, Mechanisms, and Mutations Real-world multi-ancestry sequencing uncovers germline determinants of somatic driver selection and cancer progression Room 710B/Level 7 Collaborators: Dana-Farber Cancer Institute, University of Utah CancerGenome-wide association studyGenomicsPopulation genetics Poster Fri Oct 23 2:30 pm Part of Late-Breaking Poster Friday Session Genome-wide haplotype-resolved copy number calling from utilizing on-target and off-target reads in panel sequencing Exhibit & Poster Hall · Board 4010F Collaborators: Fred Hutch Cancer Center, University of Washington Copy number/structural variationComputational toolsBioinformaticsCancer
Benjamin Greenbaum Labmskcc.org/research-areas/labs/benjamin-greenbaum Dry lab~24 people Models repetitive elements, neoantigens and tumor evolution with statistical physics and information theory. Bridges MSK Computational Oncology with the Parker Institute for Cancer Immunotherapy. 124 papers since 2024 › RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer Nature, 2025 IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer Nature, 2025 Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer Cancer Cell, 2024 Source: OpenAlex author A5063215100 Funded by The Mark Foundation for Cancer Research, Pancreatic Cancer Collective +3 more › The Mark Foundation for Cancer Research, ASPIRE Award · 2021 “The Mark Foundation for Cancer Research ASPIRE Award (2021)” Pancreatic Cancer Collective, Phillip A. Sharp Challenge Award · 2021 “Pancreatic Cancer Collective Phillip A. Sharp Challenge Award (2021)” Pershing Square Foundation, COVID-19 Award · 2020 “Pershing Square Foundation COVID-19 Award (2020)” +2 more on the lab page Source: lab pages 5 platforms and techniques › Techniques statistical physics, information theory, evolutionary biology, viral mimicry modeling, neoantigen prediction modeling Source: lab pages Currently hiring › “To learn more about available postdoctoral opportunities, please visit our Career Center” Source: lab positions page	Poster Fri Oct 23 2:30 pm Part of Cancer Poster Friday Session A body mass index polygenic score is associated with shorter progression-free survival in stage IV ovarian cancer Exhibit & Poster Hall · Board 1068F Polygenic risk scoreCancerPopulation geneticsObesity
Department of Pathology and Laboratory Medicinemskcc.org/departments/pathology-laboratory-medicine/faculty Wet + dry lab~92 people Covers pathology, laboratory medicine, molecular diagnostics and clinical bioinformatics, including clinical next-generation sequencing. Customizes patients’ treatments with other specialists based on individual diagnoses. 6 platforms and techniques › Runs Clinical next-generation sequencing (NGS) Techniques Clinical bioinformatics, Clinical proteomics, Artificial intelligence, Cytogenetics, Cell therapy Source: lab pages No funding stated · No openings posted	Talk Wed Oct 21 11:15 am Part of Clone Wars: Mutability and Its Consequences Frequency of clonal hematopoiesis mimicking constitutional variants in cancer patients undergoing genetic testing Room 710A/Level 7 CancerGenetic testingMosaicismSomatic variants
Lareau Labsloankettering.edu/research-areas/labs/caleb-lareau Wet + dry lab~6 people Reanalyzes DNA-sequencing libraries and develops PERFF-seq technology for rare-cell profiling alongside scRNA-seq. Studies human viromes, cancer immune cells and protein binders for cancer therapy. 146 papers since 2024 › FOXO1 is a master regulator of memory programming in CAR T cells Nature, 2024 Deciphering the impact of genomic variation on function Nature, 2024 Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation Immunity, 2024 Source: OpenAlex author A5054483679 Funded by NIH, K99/R00 Pathway to Independence Award +2 more › K99/R00 Pathway to Independence Award · 2022-2027 “K99/R00 Pathway to Independence Award (2022-2027)” NIH, Human Virome Program · active “our lab was recently awarded a U01 grant as part of the Human Virome Program, a new NIH-funded initiative” NCI, Ruth L. Kirschstein National Research Service Award · 2018-2020 “NCI F31- Ruth L. Kirschstein National Research Service Award (2018-2020)” +1 more on the lab page Source: lab pages 7 platforms and techniques › Works with DNA sequencing libraries, PERFF-seq, scRNA-seq Techniques Arbitrary nucleic acid cytometry, Lineage tracing, Deep-learning protein design, De novo chimeric antigen receptors Source: lab pages No openings posted	Poster Thu Oct 22 4:15 pm Part of Complex Traits and Polygenic Disorders Poster Thursday Session Heritability of unmapped DNA from biobank-scale data Exhibit & Poster Hall · Board 8250T Immune systemHeritabilityInfectious diseaseBioinformatics
Norman Labthenormanlab.com Wet + dry lab~10 people Combines Perturb-seq, single-cell CRISPR screens and computational modeling in fibroblasts. Uses them to engineer cell state for cell therapy and disease modeling. 8 papers since 2024 › Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states Nature Genetics, 2025 Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome Cell Systems, 2024 Source: OpenAlex author A5084321543 Funded by Josie Robertson Investigator, Damon Runyon Cancer Research Foundation +2 more › Josie Robertson Investigator · 2019-2024 “Josie Robertson Investigator (2019-2024)” NIH, Director's New Innovator Award · 2020 “NIH Director's New Innovator Award (2020)” Damon Runyon Cancer Research Foundation, Dale F. Frey Award for Breakthrough Scientists · 2019 “Damon Runyon-Dale F. Frey Award for Breakthrough Scientists (2019)” +1 more on the lab page Source: lab pages 10 platforms and techniques › Runs Perturb-seq, Single-cell RNA sequencing, CRISPRi/a screens, Multiome Perturb-seq Techniques Computational modeling, Genetic interaction mapping, Fibroblast models, CRISPR tool development, Epigenetic-memory measurement, In-vitro transcriptional-state engineering Source: lab pages Currently hiring › “To learn more about available postdoctoral opportunities, please visit our Career Center.” Source: lab positions page	Poster Fri Oct 23 2:30 pm Part of Late-Breaking Poster Friday Session Allele-resolved functional mapping of cancer-associated variants with BEAT-seq Exhibit & Poster Hall · Board 4002F Genome editing/CRISPRCancerGenotype-phenotype correlationsSystems biology
Offit Labmskcc.org/research-areas/labs/kenneth-offit Wet + dry lab~52 people Studies inherited cancer risk using germline genome sequencing, MSK IMPACT, CRISPR screens and organoids. Translates germline cancer genetics to the clinic. 67 papers since 2024 › Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy Nature Genetics, 2025 Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases Nature Communications, 2025 Validation of a clinical breast cancer risk assessment tool combining a polygenic score for all ancestries with traditional risk factors Genetics in Medicine, 2024 Source: OpenAlex author A5001757617 Funded by NIH, Not stated +1 more › NIH, STTR; 1 R41 CA275627-01 · active “Via an NIH STTR (1 R41 CA275627-01) with colleagues, we analyzed candidate synthetic lethal genes identified in a NER-D CRISPR screen” Not stated, R01 HG011914 01A1 · active The NIH's standard multi-year research project grant. “a clinical trial offering polygenic risk scores (PRS) to men and women with BRCA mutations (R01 HG011914 01A1), an ongoing project” Not stated, P01 CA228696 01A1 · active “Via P01 CA228696 01A1 we designed a bespoke panel for targeted sequencing of homologous repair (HR) pathways” Source: lab pages 9 platforms and techniques › Works with MSK IMPACT, Massively parallel sequencing of germline genomes, SNP genotyping Techniques Population-based statistical approaches, CRISPR screens, Organoids, Colony assays, Mendelian randomization, CRISPR-mediated enhancer deletion Source: lab pages Currently hiring › “Bioinformatics Specialist; Computational Genetics Fellow” Source: lab positions page	Poster Thu Oct 22 4:15 pm Part of Artificial Intelligence and Machine Learning Poster Thursday Session Decoding non-coding variants in the ANKRD26 5′UTR using deep learning Exhibit & Poster Hall · Board 8058T Collaborators: Boston Children's Hospital Machine learningHematopoietic systemRare variantsClinical genetics

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