ASHG 2026 · Hospital & health system

Centre for Addiction and Mental Health at ASHG 2026

Toronto, Ontario

Centre for Addiction and Mental Health at ASHG 2026 in Montréal: 7 presentations (7 posters); 4 research groups.

7
presentations on the program
4
research groups identified

Explore everyone at ASHG 2026 →

OrganizationASHG 2026 Attendance
Centre for Addiction and Mental Health
Toronto, Ontario
2 Staff Scientists · 2 Postdocs · 2 PhD Students · 1 PI
Tanenbaum Centre for Pharmacogeneticscamh.ca/en/science-and-research/institutes-and-centres/tanenbaum-centre-for-pharmacogenetics
Wet + dry lab~20 people
Studies genetic, epigenetic and gene-expression data to guide psychiatric medication response. Uses IMPACT pharmacogenetic testing and large patient cohorts for personalized mental-health treatment.
72 papers since 2024
Genomics yields biological and phenotypic insights into bipolar disorder
Nature, 2025
Mapping the genetic landscape across 14 psychiatric disorders
Nature, 2025
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder
Nature Genetics, 2024
Source: OpenAlex author A5056370228
Funded by Larry and Judy Tanenbaum, Government of Ontario +4 more
Discovery Fund · 2018
“The Discovery Fund—made possible by anonymous $100-million donation to research at CAMH in 2018—is a key driver behind these research initiatives.”
Assurex Health Ltd., CAMH-led pharmacogenetic clinical study · 2022
“Funding for the study was provided by Assurex Health Ltd. (now affiliated with Myriad Genetics), CAMH, Ontario Genomics and Genome Canada.”
Ontario Genomics, CAMH-led pharmacogenetic clinical study · 2022
“Funding for the study was provided by Assurex Health Ltd. (now affiliated with Myriad Genetics), CAMH, Ontario Genomics and Genome Canada.”
+3 more on the lab page
Source: lab pages
7 platforms and techniques
Works with
Pharmacogenetic testing, Genome-wide testing
Techniques
CRISPR/Cas technology, Machine learning, Genetics, epigenetics and gene-expression integration, Mitochondrial DNA biomarkers, Controlled clinical trials
Source: lab pages
No openings posted
Poster
Wed Oct 21
2:30 pm
Repeat Expansion Diseases and Psychiatric Disorders — a scoping review
Complex Traits and Polygenic Disorders
Collaborators: University of Toronto, University of Colorado Anschutz +2 more
Triplet and other repeats
Poster
Wed Oct 21
2:30 pm
Pharmacogenomic Variation in CYP2D6 and CYP2C19 Is Highly Prevalent in Adults with Neurodevelopmental Disorders and Associated with Increased Psychotropic Treatment Complexity
Pharmacogenomics
Collaborators: Centre for Mental Health, Keio University Hospital +1 more
PharmacogenomicsNeurodevelopmentalAutismGenetic variation
Poster
Thu Oct 22
4:15 pm
Integrating Immune Gene Expression and Polygenic Risk to Investigate Neuroimmune Mechanisms in Schizophrenia
Complex Traits and Polygenic Disorders
Polygenic risk scorePsychiatric geneticsImmune systemBrain/nervous system
Tripathy Labtriplab.org
Dry lab~14 people
Uses single-cell RNA-sequencing, spatial transcriptomics, long-read sequencing and UK Biobank data. Develops machine-learning methods for brain cell types, neurodevelopmental disorders and psychiatric illness.
32 papers since 2024
Molecular architecture of human dermal sleeping nociceptors
Cell, 2026
Genetic architecture of the structural connectome
Nature Communications, 2024
Integrating single-cell and spatially resolved transcriptomic strategies to survey the astrocyte response to stroke in male mice
Nature Communications, 2024
Source: OpenAlex author A5078768179
Funded by NSERC,
NSERC, Discovery grant · March and April 2020
Canada's base operating grant for natural-science and engineering labs, typically five years.
“funding notices for my NSERC Discovery grant”
, NeuroNex proposal · March and April 2020
“our massive, collaborative NeuroNex proposal”
Source: lab pages
10 platforms and techniques
Analyzes
single-cell RNA-sequencing, spatial transcriptomics, long-read sequencing, Patch-seq, whole-cell electrophysiology, single-nucleus RNA sequencing
Techniques
machine learning, cell type deconvolution, neuron electrophysiology, neuron morphology
Source: lab pages
Currently hiring
“We are currently looking for Masters and PhD students.”
Source: lab positions page
Poster
Thu Oct 22
4:15 pm
Ultima Genomics whole-genome sequencing identifies candidate causative variants in consanguineous families with intellectual disability
Complex Traits and Polygenic Disorders
Collaborators: Gomal University, National University of Sciences and Technology +5 more
Intellectual and developmental disabilityExome/genome sequencingSNP analysis/discoveryVariant calling
Poster
Fri Oct 23
2:30 pm
Low-Cost Whole-Genome Sequencing for Rare Variant Discovery in a Youth Psychiatric Cohort: A Pilot Study in the Toronto Adolescent and Youth (TAY) Cohort
Complex Traits and Polygenic Disorders
Psychiatric geneticsBioinformaticsRare variantsVariant calling
Pouget Labjpouget.github.io
Dry lab~7 people
Analyzes large-scale human genetic studies and sn-RNAseq plus sn-ATACseq data. Uses them to study psychosis, schizophrenia and depression in young people.
10 papers since 2024
Association study of the complement component C4 gene and suicide risk in schizophrenia
Schizophrenia, 2024
Fine-mapping the CYP2A6 regional association with nicotine metabolism among African American smokers
Molecular Psychiatry, 2024
Sex-dependent association study of complement C4 gene with treatment-resistant schizophrenia and hospitalization frequency
Psychiatry Research, 2024
Source: OpenAlex author A5060455962
Funded by CAMH
CAMH, CAMH Undergraduate Research Awards · 2026
“Congratulations to Brianna & Agam on their CAMH Undergraduate Research Awards!”
Source: lab pages
8 platforms and techniques
Analyzes
sn-RNAseq, sn-ATACseq, SNP arrays
Techniques
Mendelian randomization, polygenic risk scoring, LD Score regression, statistical fine-mapping, cell-type-specific enhancer–gene mapping
Source: lab pages
Currently hiring
“We are actively recruiting graduate students, postdoctoral research fellows, and research analysts to join our group.”
Source: lab positions page
Poster
Wed Oct 21
2:30 pm
Real-world patterns of clinical genetic testing among young people with neurodevelopmental disorders and psychosis
Health Services Research and Implementation Science
Collaborators: Holland Bloorview Kids Rehabilitation Hospital
Clinical geneticsIntellectual and developmental disabilityAutismNeurodevelopmental
Molecular Neuropsychiatry & Development (MiND) Labvincent-lab.com
Works in rare disease.
30 papers since 2024
Genomics yields biological and phenotypic insights into bipolar disorder
Nature, 2025
Fine-mapping genomic loci refines bipolar disorder risk genes
Nature Neuroscience, 2025
Biallelic variants identified in 36 Pakistani families and trios with autism spectrum disorder
Scientific Reports, 2024
Source: OpenAlex author A5036637906
Poster
Wed Oct 21
2:30 pm
Expression and stability analysis of Rett Syndrome-causing MECP2 mutations.
Complex Traits and Polygenic Disorders
Collaborators: University of Toronto
AutismNeurodevelopmentalProtein structureX-linked disease

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